概述

  • 产品名称Anti-Pirh2抗体
    参阅全部 Pirh2 一抗
  • 描述
    小鼠单克隆抗体to Pirh2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: MAATAREDGA SGQERGQRGC EHYDRGCLLK APCCDKLYTC RLCHDNNEDH QLDRFKVKEV QCINCEKIQH AQQTCEECST LFGEYYCDIC HLFDKDKKQY , corresponding to amino acids 1-101 of Human Pirh2

性能

应用

Our Abpromise guarantee covers the use of ab57152 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Contributes to the regulation of CDKN1B and p53/TP53 levels, and thereby contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
    • 通路Protein modification; protein ubiquitination.
    • 序列相似性Contains 1 CHY-type zinc finger.
      Contains 1 CTCHY-type zinc finger.
      Contains 1 RING-type zinc finger.
    • 翻译后修饰Subject to ubiquitination and proteasomal degradation. Interaction with PLAGL2 or KAT5 enhances protein stability.
    • 细胞定位Nucleus. Nucleus speckle. Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Androgen receptor N terminal interacting protein antibody
      • Androgen receptor N-terminal-interacting protein antibody
      • ARNIP antibody
      • CH-rich-interacting match with PLAG1 antibody
      • CHIMP antibody
      • E3 ubiquitin-protein ligase Pirh2 antibody
      • hARNIP antibody
      • hPirh2 antibody
      • p53 induced protein with a RING H2 domain antibody
      • p53-induced RING-H2 protein antibody
      • PIRH2E antibody
      • PIRH2F antibody
      • PRO1996 antibody
      • RCHY1 antibody
      • Ring finger and CHY zinc finger domain containing 1 E3 ubiquitin protein ligase antibody
      • RING finger and CHY zinc finger domain-containing protein 1 antibody
      • RING finger protein 199 antibody
      • RNF199 antibody
      • ZCHY antibody
      • ZFP 363 antibody
      • zinc finger CHY type antibody
      • Zinc finger protein 363 antibody
      • ZN363_HUMAN antibody
      • ZNF363 antibody
      see all

    Anti-Pirh2 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57152 Pirh2 antibody at 1ug/ml. Predicted band size of immunogen is 65 kDa

    Anti-Pirh2 antibody (ab57152)参考文献

    ab57152 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"