Anti-PIP5K1 beta抗体(ab5468)

概述

  • 产品名称Anti-PIP5K1 beta抗体
    参阅全部 PIP5K1 beta 一抗
  • 描述
    兔多克隆抗体to PIP5K1 beta
  • 经测试应用适用于: IHC-P, ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to amino acids 1-18 of Human PIP5K1 B.

  • 阳性对照
    • Human placenta cell lysate.
  • 常规说明


    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明This antibody is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.
  • Primary antibody说明Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab5468 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100.
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 61 kDa (predicted molecular weight: 64 kDa).

靶标

  • 功能Mediates RAC1-dependent reorganization of actin filaments (By similarity). Participates in the biosynthesis of phosphatidylinositol-4,5-bisphosphate.
  • 组织特异性Detected in heart, pancreas, brain, kidney, skeletal muscle and lung.
  • 序列相似性Contains 1 PIPK domain.
  • 细胞定位Endomembrane system. Associated with membranes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MSS 4 antibody
    • MSS4 antibody
    • Phosphatidylinositol 4 phosphate 5 kinase type 1 beta antibody
    • Phosphatidylinositol-4-phosphate 5-kinase type I beta antibody
    • Phosphatidylinositol-4-phosphate 5-kinase type-1 beta antibody
    • PI4P5K 1 beta antibody
    • PI51B_HUMAN antibody
    • PIP5K1-beta antibody
    • PIP5K1B antibody
    • PIP5KIbeta antibody
    • Pipk 5 beta antibody
    • Pipk 5b antibody
    • Protein STM 7 antibody
    • Protein STM-7 antibody
    • PtdIns(4)P-5-kinase 1 beta antibody
    • STM 7 antibody
    • STM7 antibody
    • STM7 LSB antibody
    • Type I phosphatidylinositol 4 phosphate 5 kinase beta antibody
    • Type I phosphatidylinositol-4-phosphate 5-kinase beta antibody
    see all

Anti-PIP5K1 beta antibody 图像



  • Predicted band size : 64 kDa


    ab5468 at a 1/100 dilution staining approximately 61kDa band of PIP5K1 B in human placenta cell lysate by Western blot (ECL).
  • ab5468 staining PIP5K1 beta in human breast carcinoma (BC) tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

Anti-PIP5K1 beta antibody (ab5468)参考文献

ab5468 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. To our knowledge, this antibody has not yet been tested for cross-reactivity with mouse. We do not routinely offer free or trial sized samples for testing purposes. Our policy at Abcam is that if an antibody does not wor...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"