概述

  • 产品名称Anti-Pin1抗体[3G8]
    参阅全部 Pin1 一抗
  • 描述
    小鼠单克隆抗体[3G8] to Pin1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1/163 of Human Pin1

  • 阳性对照
    • 293T, HeLa and Jurkat cells.

性能

应用

Our Abpromise guarantee covers the use of ab38933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 18 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzing pSer/Thr-Pro cis/trans isomerizations.
  • 序列相似性Contains 1 PpiC domain.
    Contains 1 WW domain.
  • 结构域The WW domain is required for the interaction with STIL and KIF20B.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DOD antibody
    • DODO, Drosophila, homolog of antibody
    • FLJ40239 antibody
    • FLJ77628 antibody
    • MGC10717 antibody
    • NIMA interacting 1 antibody
    • Peptidyl prolyl cis trans isomerase NIMA interacting 1 antibody
    • Peptidyl prolyl cis/trans isomerase NIMA interacting antibody
    • Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antibody
    • Peptidyl-prolyl cis-trans isomerase pin1 antibody
    • Peptidylprolyl cis/trans isomerase NIMA interacting 1 antibody
    • Pin 1 antibody
    • Pin1 antibody
    • PIN1_HUMAN antibody
    • PPIase Pin1 antibody
    • Prolyl isomerase antibody
    • Protein (peptidylprolyl cis/trans isomerase) NIMA interacting 1 antibody
    • Protein NIMA interacting 1 antibody
    • Rotamase Pin1 antibody
    • UBL 5 antibody
    • UBL5 antibody
    see all

Anti-Pin1 antibody [3G8] 图像

  • All lanes : Anti-Pin1 antibody [3G8] (ab38933) at 1/500 dilution

    Lane 1 : 293T cell lysate
    Lane 2 : HeLa cell lysate
    Lane 3 : Jurkat cell lysate

    Lysates/proteins at 50 µg per lane.

    Secondary
    goat anti-mouse secondary antibody conjugated to HRP
    Developed using the ECL technique

    Predicted band size : 18 kDa
    Observed band size : 16 kDa (why is the actual band size different from the predicted?)

Anti-Pin1 antibody [3G8] (ab38933)参考文献

ab38933 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab38933.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"