概述

  • 产品名称Anti-PIK3R5抗体
    参阅全部 PIK3R5 一抗
  • 描述
    兔多克隆抗体to PIK3R5
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide derived from a region within internal sequence of Human PIK3R5.

  • 阳性对照
    • Paraffin embedded Human colon carcinoma tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol
    Note: without Mg2+ and Ca2+
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111152 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Regulatory subunit of the PI3K gamma complex.
  • 组织特异性Ubiquitously expressed with high expression in fetal brain compared to adult brain. Abundant expression is observed in cerebellum, cerebral cortex, cerebral meninges, and vermis cerebelli.
  • 疾病相关Note=Defects in PIK3R5 may be a cause of autosomal recessive ataxia with oculomotor apraxia (AOA). A PIK3R5 mutation segregates with the disease phenotype in a family affected by gait ataxia, cerebellar dysarthric speech, and impaired ocular movement. Additional features include reduced or absent tendon reflexes, severe cerebellar atrophy, marked vermal atrophy, moderately severe axonal sensory polyneuropathy with absent sensory nerve action potential in the lower extremities, and persistently elevated alpha-fetoprotein levels.
  • 结构域The heterodimerization region allows the binding to the catalytic subunit.
  • 细胞定位Nucleus. Cytoplasm. Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5-bisphosphate 3-kinase regulatory subunit antibody
    • F730038I15Rik antibody
    • FOAP 2 antibody
    • FOAP2 antibody
    • OTTHUMP00000135339 antibody
    • p101 antibody
    • P101 PI3K antibody
    • p101-PI3K antibody
    • Phosphatidylinositol 4 antibody
    • Phosphatidylinositol 4,5 bisphosphate 3 kinase regulatory subunit antibody
    • Phosphoinositide 3 kinase, regulatory subunit 5 antibody
    • Phosphoinositide 3 kinase, regulatory subunit 5, p101 antibody
    • Phosphoinositide 3 kinase, regulatory subunit, polypeptide p101 antibody
    • Phosphoinositide 3-kinase regulatory subunit 5 antibody
    • PI3 kinase p101 subunit antibody
    • PI3 kinase regulatory subunit 5 antibody
    • PI3-kinase p101 subunit antibody
    • PI3-kinase regulatory subunit 5 antibody
    • PI3R5_HUMAN antibody
    • PIK3 R5 antibody
    • PIK3R5 antibody
    • Protein FOAP 2 antibody
    • Protein FOAP-2 antibody
    • PtdIns 3 kinase p101 antibody
    • PtdIns 3 kinase regulatory subunit antibody
    • PtdIns-3-kinase p101 antibody
    • PtdIns-3-kinase regulatory subunit antibody
    see all

Anti-PIK3R5 antibody 图像

  • ab111152, at 1/50, staining PIK3R5 in Human colon carcinoma tissue by Immunohistochemistry.

Anti-PIK3R5 antibody (ab111152)参考文献

ab111152 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111152.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"