概述

  • 产品名称Anti-PIK3R5抗体
    参阅全部 PIK3R5 一抗
  • 描述
    兔多克隆抗体to PIK3R5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog
  • 免疫原

    Synthetic peptide designed within residues: SRAQRSRSLP QPKLGTQLPS WLLAPASRPQ RRRPFLSGDE DPKASTLRVV, corresponding to internal sequence amino acids 471-520 of Human PIK3R5 (NP 055123).

  • 阳性对照
    • 293T cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab108167 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 97 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Regulatory subunit of the PI3K gamma complex.
  • 组织特异性Ubiquitously expressed with high expression in fetal brain compared to adult brain. Abundant expression is observed in cerebellum, cerebral cortex, cerebral meninges, and vermis cerebelli.
  • 疾病相关Note=Defects in PIK3R5 may be a cause of autosomal recessive ataxia with oculomotor apraxia (AOA). A PIK3R5 mutation segregates with the disease phenotype in a family affected by gait ataxia, cerebellar dysarthric speech, and impaired ocular movement. Additional features include reduced or absent tendon reflexes, severe cerebellar atrophy, marked vermal atrophy, moderately severe axonal sensory polyneuropathy with absent sensory nerve action potential in the lower extremities, and persistently elevated alpha-fetoprotein levels.
  • 结构域The heterodimerization region allows the binding to the catalytic subunit.
  • 细胞定位Nucleus. Cytoplasm. Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5-bisphosphate 3-kinase regulatory subunit antibody
    • F730038I15Rik antibody
    • FOAP 2 antibody
    • FOAP2 antibody
    • OTTHUMP00000135339 antibody
    • p101 antibody
    • P101 PI3K antibody
    • p101-PI3K antibody
    • Phosphatidylinositol 4 antibody
    • Phosphatidylinositol 4,5 bisphosphate 3 kinase regulatory subunit antibody
    • Phosphoinositide 3 kinase, regulatory subunit 5 antibody
    • Phosphoinositide 3 kinase, regulatory subunit 5, p101 antibody
    • Phosphoinositide 3 kinase, regulatory subunit, polypeptide p101 antibody
    • Phosphoinositide 3-kinase regulatory subunit 5 antibody
    • PI3 kinase p101 subunit antibody
    • PI3 kinase regulatory subunit 5 antibody
    • PI3-kinase p101 subunit antibody
    • PI3-kinase regulatory subunit 5 antibody
    • PI3R5_HUMAN antibody
    • PIK3 R5 antibody
    • PIK3R5 antibody
    • Protein FOAP 2 antibody
    • Protein FOAP-2 antibody
    • PtdIns 3 kinase p101 antibody
    • PtdIns 3 kinase regulatory subunit antibody
    • PtdIns-3-kinase p101 antibody
    • PtdIns-3-kinase regulatory subunit antibody
    see all

Anti-PIK3R5 antibody 图像

  • Anti-PIK3R5 antibody (ab108167) at 1 µg/ml + 293T cell lysate at 10 µg

    Predicted band size : 97 kDa

Anti-PIK3R5 antibody (ab108167)参考文献

ab108167 has not yet been referenced specifically in any publications.

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