Anti-PICP抗体[8] (ab17202)
Key features and details
- Mouse monoclonal [8] to PICP
- Suitable for: ELISA, IP, Sandwich ELISA
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-PICP抗体[8]
参阅全部 PICP 一抗 -
描述
小鼠单克隆抗体[8] to PICP -
宿主
Mouse -
特异性
ab17202 is specific for native PICP from amniotic fluid. -
经测试应用
适用于: ELISA, IP, Sandwich ELISAmore details -
种属反应性
与反应: Human -
免疫原
PICP purified from second trimester amniotic fluid by affinity chromatography.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS, 2.9% Sodium chloride -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
8 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab17202于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ELISA |
Use at an assay dependent concentration.
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|
IP |
Use at an assay dependent concentration.
|
|
Sandwich ELISA |
Use at an assay dependent concentration.
Use as Capture antibody with recommended pair. |
说明 |
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ELISA
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
Sandwich ELISA
Use at an assay dependent concentration. Use as Capture antibody with recommended pair. |
靶标
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功能
Type I collagen is a member of group I collagen (fibrillar forming collagen). -
组织特异性
Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite. -
疾病相关
Caffey disease
Ehlers-Danlos syndrome 1
Ehlers-Danlos syndrome 7A
Osteogenesis imperfecta 1
Osteogenesis imperfecta 2
Osteogenesis imperfecta 3
Osteogenesis imperfecta 4
Osteoporosis
A chromosomal aberration involving COL1A1 is found in dermatofibrosarcoma protuberans. Translocation t(17;22)(q22;q13) with PDGF. -
序列相似性
Belongs to the fibrillar collagen family.
Contains 1 fibrillar collagen NC1 domain.
Contains 1 VWFC domain. -
结构域
The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function. -
翻译后修饰
Proline residues at the third position of the tripeptide repeating unit (G-X-P) are hydroxylated in some or all of the chains. Proline residues at the second position of the tripeptide repeating unit (G-P-X) are hydroxylated in some of the chains.
O-linked glycan consists of a Glc-Gal disaccharide bound to the oxygen atom of a post-translationally added hydroxyl group. -
细胞定位
Secreted > extracellular space > extracellular matrix. - Information by UniProt
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数据库链接
- Entrez Gene: 1277 Human
- Omim: 120150 Human
- SwissProt: P02452 Human
- Unigene: 172928 Human
- Unigene: 681002 Human
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别名
- COL1A1 antibody
- Alpha 1 type I collagen antibody
- Alpha-1 type I collagen antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab17202 尚未被引用在任何文献中。