RabMAb

Anti-PICK1抗体[EPR4129(2)] (ab109249)

概述

  • 产品名称Anti-PICK1抗体[EPR4129(2)]
    参阅全部 PICK1 一抗
  • 描述
    兔单克隆抗体[EPR4129(2)] to PICK1
  • 经测试应用适用于: WB, IP, Flow Cytmore details
    不适用于: ICC or IHC-P
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminus of Human PICK1.

  • 阳性对照
    • Fetal brain, HeLa, LnCaP and SH-SY5Y cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

应用

Our Abpromise guarantee covers the use of ab109249 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 50 kDa (predicted molecular weight: 47 kDa).
IP 1/10 - 1/100.
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 应用说明Is unsuitable for ICC or IHC-P.
  • 靶标

    • 功能Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ACCN3/ACCN2 channel.
    • 组织特异性Ubiquitous.
    • 序列相似性Contains 1 AH domain.
      Contains 1 PDZ (DHR) domain.
    • 翻译后修饰Phosphorylation at Thr-82 appears to inhibit the interaction with AMPA receptors.
    • 细胞定位Cytoplasm > perinuclear region. Cell junction > synapse. Also present at excitatory synapses.
    • Information by UniProt
    • 数据库链接
    • 别名
      • dJ1039K5 antibody
      • MGC15204 antibody
      • OTTHUMP00000028509 antibody
      • PICK 1 antibody
      • Pick1 antibody
      • PICK1_HUMAN antibody
      • PRKCA binding protein antibody
      • PRKCA-binding protein antibody
      • PRKCABP antibody
      • Protein interacting with C kinase 1 antibody
      • Protein interacting with PRKCA antibody
      • Protein interacting with PRKCA 1 antibody
      • Protein kinase C alpha binding protein antibody
      • Protein kinase C-alpha-binding protein antibody
      • Protein that interacts with C kinase 1 antibody
      see all

    Anti-PICK1 antibody [EPR4129(2)] 图像

    • All lanes : Anti-PICK1 antibody [EPR4129(2)] (ab109249) at 1/1000 dilution

      Lane 1 : Fetal brain tissue lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : LnCaP cell lysate
      Lane 4 : SH SY5Y cell lysate


      Predicted band size : 47 kDa
      Observed band size : 50 kDa (why is the actual band size different from the predicted?)

    Anti-PICK1 antibody [EPR4129(2)] (ab109249)参考文献

    ab109249 has not yet been referenced specifically in any publications.

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