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RabMAb

Anti-PI4 kinase beta抗体[EPR3758(2)] (ab109418)

概述

  • 产品名称
    Anti-PI4 kinase beta抗体[EPR3758(2)]
    参阅全部 PI4 kinase beta 一抗
  • 描述
    兔单克隆抗体[EPR3758(2)] to PI4 kinase beta
  • 经测试应用
    适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human PI4 kinase beta.

  • 阳性对照
    • HeLa, SH-SY5Y, BxPC-3 and Jurkat cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

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应用

Our Abpromise guarantee covers the use of ab109418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 100 kDa (predicted molecular weight: 91 kDa).
  • 应用说明
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能
      Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking.
    • 组织特异性
      Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver.
    • 序列相似性
      Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
      Contains 1 PI3K/PI4K domain.
      Contains 1 PIK helical domain.
    • 细胞定位
      Endomembrane system. Mitochondrion outer membrane. Rough endoplasmic reticulum membrane. Golgi apparatus. Cytoplasm, perinuclear region. Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DKFZp686O1820 antibody
      • FLJ30129 antibody
      • NPIK antibody
      • Phosphatidylinositol 4 kinase beta antibody
      • Phosphatidylinositol 4 kinase catalytic beta antibody
      • Phosphatidylinositol 4 kinase catalytic beta polypeptide antibody
      • Phosphatidylinositol 4 kinase wortmannin sensitive antibody
      • Phosphatidylinositol 4-kinase beta antibody
      • PI4K BETA antibody
      • PI4K-beta antibody
      • PI4K92 antibody
      • PI4KB antibody
      • PI4KB_HUMAN antibody
      • PI4Kbeta antibody
      • PI4KIIIbeta antibody
      • PIK4CB antibody
      • PtdIns 4 kinase antibody
      • PtdIns 4-kinase beta antibody
      • Type III phosphatidylinositol 4 kinase beta antibody
      see all

    Anti-PI4 kinase beta antibody [EPR3758(2)] 图像

    • All lanes : Anti-PI4 kinase beta antibody [EPR3758(2)] (ab109418) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : SH-SY5Y cell lysate
      Lane 3 : BxPC-3 cell lysate
      Lane 4 : Jurkat cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 91 kDa

    实验方案

    Anti-PI4 kinase beta antibody [EPR3758(2)] (ab109418)参考文献

    This product has been referenced in:
    • Xiong Y  et al. STAT3-regulated long non-coding RNAs lnc-7SK and lnc-IGF2-AS promote hepatitis C virus replication. Mol Med Rep 12:6738-44 (2015). WB . Read more (PubMed: 26328522) »
    • Téoulé F  et al. The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication. J Virol 87:11031-46 (2013). Read more (PubMed: 23926333) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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