Anti-PI4 kinase beta抗体[EPR3758(2)] (ab109418)


  • 产品名称Anti-PI4 kinase beta抗体[EPR3758(2)]
    参阅全部 PI4 kinase beta 一抗
  • 描述
    兔单克隆抗体[EPR3758(2)] to PI4 kinase beta
  • 经测试应用适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human PI4 kinase beta.

  • 阳性对照
    • HeLa, SH-SY5Y, BxPC-3 and Jurkat cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.




Our Abpromise guarantee covers the use of ab109418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 100 kDa (predicted molecular weight: 91 kDa).
  • 应用说明Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking.
    • 组织特异性Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver.
    • 序列相似性Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
      Contains 1 PI3K/PI4K domain.
      Contains 1 PIK helical domain.
    • 细胞定位Endomembrane system. Mitochondrion outer membrane. Rough endoplasmic reticulum membrane. Golgi apparatus. Cytoplasm, perinuclear region. Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DKFZp686O1820 antibody
      • FLJ30129 antibody
      • NPIK antibody
      • Phosphatidylinositol 4 kinase beta antibody
      • Phosphatidylinositol 4 kinase catalytic beta antibody
      • Phosphatidylinositol 4 kinase catalytic beta polypeptide antibody
      • Phosphatidylinositol 4 kinase wortmannin sensitive antibody
      • Phosphatidylinositol 4-kinase beta antibody
      • PI4K BETA antibody
      • PI4K-beta antibody
      • PI4K92 antibody
      • PI4KB antibody
      • PI4KB_HUMAN antibody
      • PI4Kbeta antibody
      • PI4KIIIbeta antibody
      • PIK4CB antibody
      • PtdIns 4 kinase antibody
      • PtdIns 4-kinase beta antibody
      • Type III phosphatidylinositol 4 kinase beta antibody
      see all

    Anti-PI4 kinase beta antibody [EPR3758(2)] 图像

    • All lanes : Anti-PI4 kinase beta antibody [EPR3758(2)] (ab109418) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : SH-SY5Y cell lysate
      Lane 3 : BxPC-3 cell lysate
      Lane 4 : Jurkat cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size : 91 kDa

    Anti-PI4 kinase beta antibody [EPR3758(2)] (ab109418)参考文献

    This product has been referenced in:
    • Téoulé F  et al. The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication. J Virol 87:11031-46 (2013). Read more (PubMed: 23926333) »

    See 1 Publication for this product

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