Anti-PI4 kinase beta抗体(ab94604)

概述

  • 产品名称Anti-PI4 kinase beta抗体
    参阅全部 PI4 kinase beta 一抗
  • 描述
    兔多克隆抗体to PI4 kinase beta
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 252-301 (ILSDELKPAH RKRELPSLSP APDTGLSPSK RTHQRSKSDA TASISLSSNL) of Human PI4 kinase beta (NP_002642).

  • 阳性对照
    • Jurkat cell lysate

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab94604 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 91 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking.
  • 组织特异性Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver.
  • 序列相似性Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
    Contains 1 PI3K/PI4K domain.
    Contains 1 PIK helical domain.
  • 细胞定位Endomembrane system. Mitochondrion outer membrane. Rough endoplasmic reticulum membrane. Golgi apparatus. Cytoplasm, perinuclear region. Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp686O1820 antibody
    • FLJ30129 antibody
    • NPIK antibody
    • Phosphatidylinositol 4 kinase beta antibody
    • Phosphatidylinositol 4 kinase catalytic beta antibody
    • Phosphatidylinositol 4 kinase catalytic beta polypeptide antibody
    • Phosphatidylinositol 4 kinase wortmannin sensitive antibody
    • Phosphatidylinositol 4-kinase beta antibody
    • PI4K BETA antibody
    • PI4K-beta antibody
    • PI4K92 antibody
    • PI4KB antibody
    • PI4KB_HUMAN antibody
    • PI4Kbeta antibody
    • PI4KIIIbeta antibody
    • PIK4CB antibody
    • PtdIns 4 kinase antibody
    • PtdIns 4-kinase beta antibody
    • Type III phosphatidylinositol 4 kinase beta antibody
    see all

Anti-PI4 kinase beta antibody 图像

  • Anti-PI4 kinase beta antibody (ab94604) at 1 µg/ml (in 5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 91 kDa

Anti-PI4 kinase beta antibody (ab94604)参考文献

ab94604 has not yet been referenced specifically in any publications.

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