Anti-PI 3 Kinase p55 gamma抗体(ab97862)
Key features and details
- Rabbit polyclonal to PI 3 Kinase p55 gamma
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-PI 3 Kinase p55 gamma抗体
参阅全部 PI 3 Kinase p55 gamma 一抗 -
描述
兔多克隆抗体to PI 3 Kinase p55 gamma -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow -
免疫原
Recombinant fragment, corresponding to a sequence within amino acids 242-437 of Human PI 3 Kinase p55 gamma (AAH21622).
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阳性对照
- 293T, H1299, HeLaS3, HepG2, MOLT4 and Raji cell lysates; A431 whole cell lysate. SAS xenograft tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab97862于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
1/100 - 1/500.
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WB |
1/500 - 1/3000. Predicted molecular weight: 54 kDa.
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说明 |
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IHC-P
1/100 - 1/500. |
WB
1/500 - 1/3000. Predicted molecular weight: 54 kDa. |
靶标
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功能
Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. -
组织特异性
Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle. -
序列相似性
Belongs to the PI3K p85 subunit family.
Contains 2 SH2 domains. - Information by UniProt
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数据库链接
- Entrez Gene: 286865 Cow
- Entrez Gene: 8503 Human
- Entrez Gene: 18710 Mouse
- Entrez Gene: 60664 Rat
- Omim: 606076 Human
- SwissProt: O46404 Cow
- SwissProt: Q92569 Human
- SwissProt: Q64143 Mouse
see all -
别名
- DKFZp686P05226 antibody
- FLJ41892 antibody
- OTTHUMP00000009783 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab97862 被引用在 3 文献中.
- Xu H et al. CircRNA_0000392 promotes colorectal cancer progression through the miR-193a-5p/PIK3R3/AKT axis. J Exp Clin Cancer Res 39:283 (2020). PubMed: 33317596
- Peng YP et al. PIK3R3 Promotes Metastasis of Pancreatic Cancer via ZEB1 Induced Epithelial-Mesenchymal Transition. Cell Physiol Biochem 46:1930-1938 (2018). PubMed: 29719293
- Mei Q et al. Genetic and Methylation-Induced Loss of miR-181a2/181b2 within chr9q33.3 Facilitates Tumor Growth of Cervical Cancer through the PIK3R3/Akt/FoxO Signaling Pathway. Clin Cancer Res 23:575-586 (2017). PubMed: 27503199