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RabMAb

Anti-PI 3 Kinase p110 delta抗体[Y387] (ab32401)

概述

  • 产品名称
    Anti-PI 3 Kinase p110 delta抗体[Y387]
    参阅全部 PI 3 Kinase p110 delta 一抗
  • 描述
    兔单克隆抗体[Y387] to PI 3 Kinase p110 delta
  • 特异性
    ab32401 recognises PI3-Kinases (PI3-Ks).
  • 经测试应用
    适用于: WB, ICC/IF, IPmore details
    不适用于: Flow Cyt or IHC
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide of human PI3-K p110 delta.

  • 阳性对照
    • Jurkat cell lysate and HeLa cells.
  • 常规说明

     

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab32401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500. Detects a band of approximately 110 kDa (predicted molecular weight: 119 kDa).
ICC/IF 1/250 - 1/500.
IP 1/50.
  • 应用说明
    Is unsuitable for Flow Cyt or IHC.
  • 靶标

    • 组织特异性
      Expressed predominantly in leukocytes.
    • 通路
      Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.
    • 序列相似性
      Belongs to the PI3/PI4-kinase family.
      Contains 1 PI3K/PI4K domain.
    • 翻译后修饰
      Autophosphorylation on Ser-1039 results in the almost complete inactivation of the lipid kinase activity.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta antibody
      • 5-bisphosphate 3-kinase catalytic subunit delta isoform antibody
      • APDS antibody
      • GRB1 antibody
      • IMD14 antibody
      • p110d antibody
      • p110delta antibody
      • p110dp85a antibody
      • p85-ALPHA antibody
      • Phosphatidylinositol 3 kinase catalytic delta polypeptide antibody
      • Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform antibody
      • Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta antibody
      • Phosphatidylinositol 4,5 bisphosphate 3 kinase, catalytic subunit delta antibody
      • Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform antibody
      • Phosphatidylinositol-4 antibody
      • Phosphoinositide 3 kinase B antibody
      • Phosphoinositide 3 kinase C antibody
      • Phosphoinositide 3 kinase catalytic delta polypeptide antibody
      • Phosphoinositide 3 kinase, catalytic, delta polypeptide variant p37delta antibody
      • PI3 kinase p110 subunit delta antibody
      • PI3-kinase subunit delta antibody
      • PI3K antibody
      • PI3K-delta antibody
      • PI3Kdelta antibody
      • Pik3cd antibody
      • PIK3R1 antibody
      • PK3CD antibody
      • PK3CD_HUMAN antibody
      • PtdIns 3 kinase p110 antibody
      • PtdIns 3 kinase subunit p110 delta antibody
      • PtdIns-3-kinase subunit delta antibody
      • PtdIns-3-kinase subunit p110-delta antibody
      see all

    图片

    • Anti-PI 3 Kinase p110 delta antibody [Y387] (ab32401) at 1/500 dilution + Jurkat cell lysate

      Predicted band size : 119 kDa
      Observed band size : 110 kDa (why is the actual band size different from the predicted?)
    • Immunofluorescent staining of HeLa cells using ab32401 at 1/250 dilution.

    文献

    This product has been referenced in:
    • Milara J  et al. Non-neuronal cholinergic system contributes to corticosteroid resistance in chronic obstructive pulmonary disease patients. Respir Res 17:145 (2016). IP ; Human . Read more (PubMed: 27825347) »
    • Mendizabal-Zubiaga J  et al. Cannabinoid CB1 Receptors Are Localized in Striated Muscle Mitochondria and Regulate Mitochondrial Respiration. Front Physiol 7:476 (2016). IP ; Mouse . Read more (PubMed: 27826249) »

    See all 10 Publications for this product

    客户评价及客户问答

    Thank you for contacting us.
    I am sorry to hear that the antibodies for PI3K p110 delta do not seem to work as expected.

    As we discussed over the phone, I would like to suggest to try the following:

    1) Load moreprotein onto th...

    Read More

    I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has caused. As requested, I have issued a free of charge replacement for one vial of ab109006. To check the status of the order please contact our Custome...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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