RabMAb

Anti-PI 3 Kinase p110 delta抗体[Y387] (ab32401)

概述

  • 产品名称Anti-PI 3 Kinase p110 delta抗体[Y387]
    参阅全部 PI 3 Kinase p110 delta 一抗
  • 描述
    兔单克隆抗体[Y387] to PI 3 Kinase p110 delta
  • 特异性ab32401 recognises PI3-Kinases (PI3-Ks).
  • 经测试应用适用于: WB, ICC/IF, IPmore details
    不适用于: Flow Cyt or IHC
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide of human PI3-K p110 delta.

  • 阳性对照
    • Jurkat cell lysate and HeLa cells.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab32401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500. Detects a band of approximately 110 kDa (predicted molecular weight: 119 kDa).
ICC/IF 1/250 - 1/500.
IP 1/50.
  • 应用说明Is unsuitable for Flow Cyt or IHC.
  • 靶标

    • 组织特异性Expressed predominantly in leukocytes.
    • 通路Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.
    • 序列相似性Belongs to the PI3/PI4-kinase family.
      Contains 1 PI3K/PI4K domain.
    • 翻译后修饰Autophosphorylation on Ser-1039 results in the almost complete inactivation of the lipid kinase activity.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta antibody
      • 5-bisphosphate 3-kinase catalytic subunit delta isoform antibody
      • APDS antibody
      • GRB1 antibody
      • IMD14 antibody
      • p110d antibody
      • p110delta antibody
      • p110dp85a antibody
      • p85-ALPHA antibody
      • Phosphatidylinositol 3 kinase catalytic delta polypeptide antibody
      • Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform antibody
      • Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta antibody
      • Phosphatidylinositol 4,5 bisphosphate 3 kinase, catalytic subunit delta antibody
      • Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform antibody
      • Phosphatidylinositol-4 antibody
      • Phosphoinositide 3 kinase B antibody
      • Phosphoinositide 3 kinase C antibody
      • Phosphoinositide 3 kinase catalytic delta polypeptide antibody
      • Phosphoinositide 3 kinase, catalytic, delta polypeptide variant p37delta antibody
      • PI3 kinase p110 subunit delta antibody
      • PI3-kinase subunit delta antibody
      • PI3K antibody
      • PI3K-delta antibody
      • PI3Kdelta antibody
      • Pik3cd antibody
      • PIK3R1 antibody
      • PK3CD antibody
      • PK3CD_HUMAN antibody
      • PtdIns 3 kinase p110 antibody
      • PtdIns 3 kinase subunit p110 delta antibody
      • PtdIns-3-kinase subunit delta antibody
      • PtdIns-3-kinase subunit p110-delta antibody
      see all

    Anti-PI 3 Kinase p110 delta antibody [Y387] 图像

    • Anti-PI 3 Kinase p110 delta antibody [Y387] (ab32401) at 1/500 dilution + Jurkat cell lysate

      Predicted band size : 119 kDa
      Observed band size : 110 kDa (why is the actual band size different from the predicted?)
    • Immunofluorescent staining of HeLa cells using ab32401 at 1/250 dilution.

    Anti-PI 3 Kinase p110 delta antibody [Y387] (ab32401)参考文献

    This product has been referenced in:
    • Conte E  et al. PI3K p110? overexpression in idiopathic pulmonary fibrosis lung tissue and fibroblast cells: in vitro effects of its inhibition. Lab Invest 93:566-76 (2013). WB ; Human . Read more (PubMed: 23439433) »
    • Law AJ  et al. Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110d inhibition as a potential therapeutic strategy. Proc Natl Acad Sci U S A 109:12165-70 (2012). Read more (PubMed: 22689948) »

    See all 6 Publications for this product

    Product Wall

    Thank you for contacting us.
    I am sorry to hear that the antibodies for PI3K p110 delta do not seem to work as expected.

    As we discussed over the phone, I would like to suggest to try the following:

    1) Load moreprotein onto th...

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    I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has caused. As requested, I have issued a free of charge replacement for one vial of ab109006. To check the status of the order please contact our Custome...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"