Anti-PI 3 Kinase Class 3抗体(ab73262)

概述

  • 产品名称Anti-PI 3 Kinase Class 3抗体
    参阅全部 PI 3 Kinase Class 3 一抗
  • 描述
    兔多克隆抗体to PI 3 Kinase Class 3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Pig, Xenopus laevis
  • 免疫原

    Synthetic peptide corresponding to an internal portion within amino acids 700-850 of Human PI 3 Kinase Class 3.

  • 阳性对照
    • HepG2 Whole Cell Lysates.

性能

应用

Our Abpromise guarantee covers the use of ab73262 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).

靶标

  • 功能Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis.
  • 组织特异性Ubiquitously expressed, with a highest expression in skeletal muscle.
  • 序列相似性Belongs to the PI3/PI4-kinase family.
    Contains 1 PI3K/PI4K domain.
  • 细胞定位Midbody.
  • Information by UniProt
  • 数据库链接
  • 别名
    • hVps34 antibody
    • MGC61518 antibody
    • Phosphatidylinositol 3 kinase catalytic subunit type 3 antibody
    • Phosphatidylinositol 3 kinase class 3 antibody
    • Phosphatidylinositol 3 kinase p100 subunit antibody
    • Phosphatidylinositol 3-kinase catalytic subunit type 3 antibody
    • Phosphatidylinositol 3-kinase p100 subunit antibody
    • Phosphoinositide 3 kinase class 3 antibody
    • Phosphoinositide-3-kinase class 3 antibody
    • PI3 kinase type 3 antibody
    • PI3-kinase type 3 antibody
    • PI3K type 3 antibody
    • Pik3c3 antibody
    • PK3C3_HUMAN antibody
    • PtdIns 3 kinase type 3 antibody
    • PtdIns-3-kinase type 3 antibody
    • Vps 34 antibody
    • Vps34 antibody
    see all

Anti-PI 3 Kinase Class 3 antibody 图像

  • Anti-PI 3 Kinase Class 3 antibody (ab73262) at 1/1000 dilution + HepG2 whole cell lysates

    Predicted band size : 102 kDa
    Observed band size : 102 kDa

Anti-PI 3 Kinase Class 3 antibody (ab73262)参考文献

This product has been referenced in:
  • Lian J  et al. A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum. Cell Death Differ 18:60-71 (2011). Read more (PubMed: 20577262) »

See 1 Publication for this product

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (HeLa)
Specification HeLa
Fixative Paraformaldehyde
Permeabilization Yes - 0.5% TritonX100 in PBS
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Dr. Kirk McManus

Verified customer

提交于 Nov 16 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"