Anti-Phosphotyrosine抗体[PT-66] (Biotin) (ab49667)

概述

  • 产品名称Anti-Phosphotyrosine抗体[PT-66] (Biotin)
    参阅全部 Phosphotyrosine 一抗
  • 描述
    小鼠单克隆抗体[PT-66] to Phosphotyrosine (Biotin)
  • 偶联物Biotin
  • 特异性This antibody reacts specifically with phosphorylated tyrosine, both as free amino acid or conjugated to carriers such as BSA or KLH. No cross-reactivity is observed with non-phosphorylated tyrosine, phosphothreonine, phosphoserine, AMP or ATP.
  • 经测试应用适用于: ELISA, Dot blotmore details
  • 种属反应性
    与反应: Species independent
  • 免疫原

    Phosphotyrosine conjugated to BSA

性能

应用

Our Abpromise guarantee covers the use of ab49667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/50000.
Dot blot 1/32000.

靶标

  • 相关性The phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine phosphorylated proteins and the biochemical pathways in which they function.

Anti-Phosphotyrosine antibody [PT-66] (Biotin) (ab49667)参考文献

This product has been referenced in:
  • Dvir A  et al. The inhibition of EGF-dependent proliferation of keratinocytes by tyrphostin tyrosine kinase blockers. J Cell Biol 113:857-65 (1991). Read more (PubMed: 1709168) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"