概述

  • 产品名称Anti-Phosphotyrosine抗体[P-TYR-01]
    参阅全部 Phosphotyrosine 一抗
  • 描述
    小鼠单克隆抗体[P-TYR-01] to Phosphotyrosine
  • 特异性Phosphotyrosine.
  • 经测试应用适用于: ICC, WBmore details
  • 种属反应性
    与反应: Species independent
  • 免疫原

    Phosphotyrosine conjugated to BSA.

  • 阳性对照
    • Jurkat cells stimulated with anti CD3 antibody (2 min incubation).

性能

应用

Our Abpromise guarantee covers the use of ab8076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC
WB
  • 应用说明ICC: Use at an assay dependant dilution.
    WB: Use at an assay dependant concentration.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性The phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine phosphorylated proteins and the biochemical pathways in which they function.

    Anti-Phosphotyrosine antibody [P-TYR-01] (ab8076)参考文献

    This product has been referenced in:
    • Saxinger C  et al. Fully automated synthesis of (phospho)peptide arrays in microtiter plate wells provides efficient access to protein tyrosine kinase characterization. BMC Immunol 6:1 (2005). Read more (PubMed: 15647109) »
    • Brdicka T  et al. Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation. J Exp Med 191:1591-604 (2000). Read more (PubMed: 10790433) »

    See all 4 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"