Anti-Phosphotyrosine抗体[2Q267] (ab17285)

概述

  • 产品名称Anti-Phosphotyrosine抗体[2Q267]
    参阅全部 Phosphotyrosine 一抗
  • 描述
    小鼠单克隆抗体[2Q267] to Phosphotyrosine
  • 特异性Binds specifically and with a high affinity to proteins with phosphorylated tyrosine residues. Binding can be blocked by phosphotyrosine and phenyl phosphate (IC50:10e-6M, ELISA). Does not crossreact with tyrosine, phosphoserine, phosphothreonine, sulphotyrosine (sulfated (23-25) cholecystokinine) or Na-benzoate
  • 经测试应用适用于: ELISA, WB, IP, ICCmore details
  • 种属反应性
    与反应: Species independent
  • 免疫原

    Chemical/ Small Molecule (Hapten O-phopshotyramine)

性能

应用

Our Abpromise guarantee covers the use of ab17285 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
WB Use a concentration of 0.4 - 1 µg/ml.
IP Use a concentration of 100 µg/ml.
ICC Use a concentration of 5 - 10 µg/ml.

靶标

  • 相关性The phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine phosphorylated proteins and the biochemical pathways in which they function.

Anti-Phosphotyrosine antibody [2Q267] (ab17285)参考文献

ab17285 has not yet been referenced specifically in any publications.

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