Anti-Phosphoserine phosphatase抗体(ab98186)

概述

  • 产品名称
    Anti-Phosphoserine phosphatase抗体
    参阅全部 Phosphoserine phosphatase 一抗
  • 描述
    兔多克隆抗体to Phosphoserine phosphatase
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Sheep, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 175-224,

    IMIGDGATDMEACPPADAFIGFGGNVIRQQVKDNAKWYITDFVELLGELE

    , of Human Phosphoserine phosphatase (NP_004568).

  • 阳性对照
    • Human Fetal Heart Lysate

性能

应用

Our Abpromise guarantee covers the use of ab98186 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates.
  • 通路
    Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.
  • 疾病相关
    Defects in PSPH are the cause of phosphoserine phosphatase deficiency (PSPHD)[MIM:614023]. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.
  • 序列相似性
    Belongs to the SerB family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EC 3.1.3.3 antibody
    • L 3 phosphoserine phosphatase antibody
    • L-3-phosphoserine phosphatase antibody
    • O phosphoserine phosphohydrolase antibody
    • O-phosphoserine phosphohydrolase antibody
    • Phosphoserine phosphatase antibody
    • Phosphoserine phosphatase deficiency, included antibody
    • PSP antibody
    • PSPase antibody
    • Psph antibody
    • PSPHD antibody
    • SERB_HUMAN antibody
    see all

图片

  • Anti-Phosphoserine phosphatase antibody (ab98186) at 1 µg/ml (n 5% skim milk / PBS buffer) + Human Fetal Heart Lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 25 kDa

实验方案

文献

ab98186 has not yet been referenced specifically in any publications.

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