Anti-Phosphorylase B抗体(ab69586)

概述

  • 产品名称Anti-Phosphorylase B抗体
    参阅全部 Phosphorylase B 一抗
  • 描述
    兔多克隆抗体to Phosphorylase B
  • 特异性Detects endogenous levels of Phosphorylase B protein.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthesized peptide derived from internal of human Phosphorylase B

  • 阳性对照
    • Extracts from K562 cells

性能

应用

Our Abpromise guarantee covers the use of ab69586 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 121 kDa (predicted molecular weight: 121 kDa).
ELISA 1/40000.

靶标

  • 功能Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
  • 通路Glycan biosynthesis; glycogen metabolism.
  • 疾病相关Glycogen storage disease 9B
  • 序列相似性Belongs to the phosphorylase b kinase regulatory chain family.
  • 翻译后修饰Ser-701 is probably phosphorylated by PKA.
    Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp781E15103 antibody
    • FLJ41698 antibody
    • KPBB_HUMAN antibody
    • PHKB antibody
    • Phosphorylase b kinase regulatory subunit beta antibody
    • Phosphorylase kinase B antibody
    • Phosphorylase kinase beta polypeptide antibody
    • Phosphorylase kinase beta subunit antibody
    • Phosphorylase kinase subunit beta antibody
    see all

Anti-Phosphorylase B antibody 图像

  • All lanes : Anti-Phosphorylase B antibody (ab69586) at 1/500 dilution

    Lane 1 : extracts from K562 cells, without immunising peptide
    Lane 2 : extracts from K562 cells, with immunising peptide

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 121 kDa
    Observed band size : 121 kDa

Anti-Phosphorylase B antibody (ab69586)参考文献

ab69586 has not yet been referenced specifically in any publications.

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