Anti-Phosphorylase B抗体(ab31121)

概述

  • 产品名称
    Anti-Phosphorylase B抗体
    参阅全部 Phosphorylase B 一抗
  • 描述
    羊多克隆抗体to Phosphorylase B
  • 特异性
    Recognizes Phosphorylase B. Exhibits high crossreactivity (95-135%) with Phosphorylase A by ELISA.
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Rabbit
  • 免疫原

    Full length native protein: Phosphorylase B from rabbit muscle

性能

应用

Our Abpromise guarantee covers the use of ab31121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/300 - 1/1000.
WB 1/500 - 1/1000. Predicted molecular weight: 121 kDa.

靶标

  • 功能
    Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
  • 通路
    Glycan biosynthesis; glycogen metabolism.
  • 疾病相关
    Glycogen storage disease 9B
  • 序列相似性
    Belongs to the phosphorylase b kinase regulatory chain family.
  • 翻译后修饰
    Ser-701 is probably phosphorylated by PKA.
    Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 别名
    • DKFZp781E15103 antibody
    • FLJ41698 antibody
    • KPBB_HUMAN antibody
    • PHKB antibody
    • Phosphorylase b kinase regulatory subunit beta antibody
    • Phosphorylase kinase B antibody
    • Phosphorylase kinase beta polypeptide antibody
    • Phosphorylase kinase beta subunit antibody
    • Phosphorylase kinase subunit beta antibody
    see all

实验方案

文献

ab31121 has not yet been referenced specifically in any publications.

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