Anti-Phospholipase D1 (phospho S561)抗体(ab60993)

概述

  • 产品名称Anti-Phospholipase D1 (phospho S561)抗体
    参阅全部 Phospholipase D1 一抗
  • 描述
    兔多克隆抗体to Phospholipase D1 (phospho S561)
  • 特异性Detects endogenous levels of Phospholipase D1 (PLD1) only when phosphorylated at serine 561.
  • 经测试应用适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic phosphopeptide derived from human Phospholipase D1 around the phosphorylation site of serine 561 (K-F-SP-L-Y).

  • 阳性对照
    • Brain tissue

性能

应用

Our Abpromise guarantee covers the use of ab60993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/5000.
IHC-P 1/50 - 1/100.

靶标

  • 功能Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic.
  • 组织特异性Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine.
  • 序列相似性Belongs to the phospholipase D family.
    Contains 1 PH domain.
    Contains 2 PLD phosphodiesterase domains.
    Contains 1 PX (phox homology) domain.
  • 细胞定位Cytoplasm > perinuclear region. Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Choline phosphatase 1 antibody
    • hPLD1 antibody
    • Phosphatidylcholine-hydrolyzing phospholipase D1 antibody
    • Phospholipase D1 antibody
    • PLD 1 antibody
    • PLD1 antibody
    • PLD1_HUMAN antibody
    see all

Anti-Phospholipase D1 (phospho S561) antibody 图像

  • Human brain tissue stained for Phospholipase D1 with ab60993 at 1/50-1/100 dilution, in the presence (right) or absence (left) of the immunizing phosphopeptide.

Anti-Phospholipase D1 (phospho S561) antibody (ab60993)参考文献

ab60993 has not yet been referenced specifically in any publications.

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