概述

  • 产品名称Anti-Phospholipase A2 X抗体
    参阅全部 Phospholipase A2 X 一抗
  • 描述
    兔多克隆抗体to Phospholipase A2 X
  • 特异性This antibody is specific for Phospholipase A2 X.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant human Phospholipase A2 X. A 15.5 kDa protein containing 123 amino acid residues of the human Phospholipase A2 X and 16 additional amino acid residues, HisTag. Source of immunogen, E.coli

性能

应用

Our Abpromise guarantee covers the use of ab47111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 17 kDa.

靶标

  • 功能PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Has a powerful potency for releasing arachidonic acid from cell membrane phospholipids. Prefers phosphatidylethanolamine and phosphatidylcholine liposomes to those of phosphatidylserine.
  • 组织特异性Found in spleen, thymus, peripheral blood leukocytes, pancreas, lung, and colon.
  • 序列相似性Belongs to the phospholipase A2 family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Group 10 secretory phospholipase A2 antibody
    • Group X secretory phospholipase A2 antibody
    • GX sPLA2 antibody
    • GXPLA2 antibody
    • GXSPLA2 antibody
    • PA2GX_HUMAN antibody
    • Phosphatidylcholine 2 acylhydrolase GX antibody
    • Phosphatidylcholine 2-acylhydrolase 10 antibody
    • Phospholipase A2 group X antibody
    • PLA2G10 antibody
    • SPLA2 antibody
    • sPLA2-X antibody
    • sPLA2X antibody
    see all

Anti-Phospholipase A2 X antibody 图像

  • All lanes : Anti-Phospholipase A2 X antibody (ab47111) at 1 µg/ml

    Lane 1 : Whole cell extracts from RAW264.7 control cells
    Lane 2 : Whole cell extracts from RAW264.7 cells overexpressing Phospholipase A2 X

    Lysates/proteins at 20 µg per lane.

    Secondary
    Horseradish peroxidase-conjugated secondary antibody

    Predicted band size : 17 kDa
    Observed band size : 17 kDa

    Image from Curfs DM et al, J Biol Chem. 2008 Aug 1;283(31):21640-8. Epub 2008 May 28, Fig 1.DOI 10.1074/jbc.M710584200

Anti-Phospholipase A2 X antibody (ab47111)参考文献

This product has been referenced in:
  • Curfs DM  et al. Macrophage Secretory Phospholipase A2 Group X Enhances Anti-inflammatory Responses, Promotes Lipid Accumulation, and Contributes to Aberrant Lung Pathology. J Biol Chem 283:21640-8 (2008). WB ; Human . Read more (PubMed: 18511424) »

See 1 Publication for this product

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