Anti-Phosphatidic acid phosphatase type 2B抗体[ZV002] (ab52581)

概述

  • 产品名称Anti-Phosphatidic acid phosphatase type 2B抗体[ZV002]
    参阅全部 Phosphatidic acid phosphatase type 2B 一抗
  • 描述
    小鼠单克隆抗体[ZV002] to Phosphatidic acid phosphatase type 2B
  • 特异性This antibody is specific for the ~33-35 kDa human VCIP (vascular endothelial growth factor and type I collagen inducible protein, phosphatidic acid phosphatase 2b, PAP2b) protein.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant protein derived from an internal region of human PPAP2b.

  • 阳性对照
    • Human PPAP2b-transfected 293 cells.

性能

应用

Our Abpromise guarantee covers the use of ab52581 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 35 kDa.
ELISA Use a concentration of 0.1 - 1 µg/ml.

靶标

  • 功能Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA = PA > C-1-P > S-1-P. May be involved in cell adhesion and in cell-cell interactions.
  • 组织特异性Ubiquitously expressed. Highly expressed in heart and placenta.
  • 序列相似性Belongs to the PA-phosphatase related phosphoesterase family.
  • 翻译后修饰N-glycosylated. Contains high-mannose oligosaccharides.
  • 细胞定位Golgi apparatus > trans-Golgi network membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Dri 42 antibody
    • Dri42 antibody
    • Lipid phosphate phosphohydrolase 3 antibody
    • LPP3 antibody
    • LPP3_HUMAN antibody
    • PAP 2b antibody
    • PAP-2b antibody
    • PAP2 beta antibody
    • PAP2-beta antibody
    • PAP2b antibody
    • Phosphatidate phosphohydrolase type 2b antibody
    • Phosphatidic acid phosphatase 2b antibody
    • Ppap2b antibody
    • type 2 phosphatidic acid phosphatase beta antibody
    • vascular endothelial growth factor and type I collagen inducible antibody
    • Vascular endothelial growth factor and type I collagen inducible protein antibody
    • Vascular endothelial growth factor and type I collagen-inducible protein antibody
    • VCIP antibody
    see all

Anti-Phosphatidic acid phosphatase type 2B antibody [ZV002] (ab52581)参考文献

ab52581 has not yet been referenced specifically in any publications.

Product Wall

I have just received a reply from the originator of the antibody, I hope this will also help you: "VCIP is also called PPAP2B: phosphatidic acid phosphatase type 2B. The protein encoded by this gene is a member of the phosphatidic acid phosphatase (...

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Thank you for contacting us for technical support with ab52581. This antibody has so far not been tested in mouse samples though due to good homology of the immunogen with mouse PAP2B we would predict the antibody to cross react with the mouse prote...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"