概述

  • 产品名称Anti-PHF17抗体
    参阅全部 PHF17 一抗
  • 描述
    小鼠多克隆抗体to PHF17
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length PHF17 protein (Human)

  • 阳性对照
    • Hela cells and 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab66968 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 65 kDa (predicted molecular weight: 96 kDa).
ICC/IF Use a concentration of 10 µg/ml. Requires purification with Protein A prior to ICC/IF.

靶标

  • 功能Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.
  • 组织特异性Highly expressed in kidney. Also present in pancreas, liver and heart (at protein level). Down-regulated in renal cancer cells.
  • 序列相似性Belongs to the JADE family.
    Contains 2 PHD-type zinc fingers.
  • 结构域The 2 PHD-type zinc fingers are required for transcriptional activity.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ22479 antibody
    • Gene for apoptosis and differentiation in epithelia antibody
    • JADE1 antibody
    • JADE1_HUMAN antibody
    • KIAA1807 antibody
    • OTTHUMP00000219842 antibody
    • OTTHUMP00000219934 antibody
    • OTTHUMP00000219935 antibody
    • OTTHUMP00000219936 antibody
    • PHD finger protein 17 antibody
    • PHD protein Jade 1 antibody
    • Phf17 antibody
    • Protein Jade 1 antibody
    • Protein Jade-1 antibody
    see all

Anti-PHF17 antibody 图像

  • Immunofluorescence of ab66968 on HeLa cells. (purified antibody concentration of 10ug/ml)
  • All lanes : Anti-PHF17 antibody (ab66968) at 1/500 dilution

    Lane 1 : PHF17 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 96 kDa
    Observed band size : 65 kDa (why is the actual band size different from the predicted?)

Anti-PHF17 antibody (ab66968)参考文献

ab66968 has not yet been referenced specifically in any publications.

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