概述

  • 产品名称Anti-PHEMX抗体
  • 描述
    兔多克隆抗体to PHEMX
  • 特异性ab65539 reacts with PHEMX isoform 2.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Horse
  • 免疫原

    A region within synthetic peptide: QGEEAAREDC LQGIRSFLRT HQQVASSLTS IGLALTVSAL LFSSFLWFAI, corresponding to internal sequence amino acids 144-193 of Human PHEMX

  • 阳性对照
    • HepG2 cell lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab65539 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/1562500.

WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 31 kDa (predicted molecular weight: 31 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性PHEMX belongs to the conserved tetraspanin family of integral membrane proteins, which are thought to form multiprotein networks in the cell membrane in association with multiple protein partners. Tetraspanins have functional roles in cell motility, membrane fusion, proliferation, and adaptive immunity. This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. PHEMX may play a role in malignancies and disease that involve this region as well as hematopoietic cell function. There are 5 isoforms produced by alternative splicing.
  • 细胞定位Membrane; Multi-pass membrane protein
  • 数据库链接
  • 别名
    • ART1 antibody
    • FLJ17158 antibody
    • FLJ97586 antibody
    • MGC22455 antibody
    • Pan hematopoietic expression antibody
    • PHEMX antibody
    • PHMX antibody
    • tetraspanin 32 antibody
    • Tetraspanin antibody
    • tetraspanin32 antibody
    • TSPAN32 antibody
    • TSSC6 antibody
    • Tumor suppressing STF cDNA 6 antibody
    • Tumor suppressing subchromosomal transferable fragment cDNA 6 antibody
    • Tumor suppressing subtransferable candidate 6 antibody
    see all

Anti-PHEMX antibody 图像

  • Anti-PHEMX antibody (ab65539) at 2.5 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 31 kDa
    Observed band size : 31 kDa

Anti-PHEMX antibody (ab65539)参考文献

ab65539 has not yet been referenced specifically in any publications.

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