Anti-PHD finger protein 6抗体(ab111844)

概述

  • 产品名称Anti-PHD finger protein 6抗体
    参阅全部 PHD finger protein 6 一抗
  • 描述
    兔多克隆抗体to PHD finger protein 6
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow, Pig
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 66-251 of Human PHD finger protein 6 (AAH05994).

  • 阳性对照
    • NT2D1, IMR32, U-87 MG, MCF7 cells and whole cell lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 78.99% PBS, 1% BSA, 20% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab111844 is purified by antigen-affinity chromatography.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111844 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 35 kDa.
ICC/IF 1/100 - 1/500.

靶标

  • 功能May play a role in transcriptional regulation.
  • 组织特异性Ubiquitously expressed.
  • 疾病相关Defects in PHF6 are the cause of Boerjeson-Forssman-Lehmann syndrome (BFLS) [MIM:301900]; also known as Boerjeson-Forssman syndrome (BORJ). BFLS is a X-linked recessive disorder characterized by moderate to severe mental retardation, epilepsy, hypogonadism, hypometabolism, obesity with marked gynecomastia, swelling of subcutaneous tissue of the face, narrow palpebral fissure and large but not deformed ears.
  • 序列相似性Contains 2 PHD-type zinc fingers.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus. Nucleus > nucleolus. Nuclear, it particularly localizes to the nucleolus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AC004383.6 antibody
    • BFLS antibody
    • BORJ antibody
    • CENP 31 antibody
    • Centromere protein 31 antibody
    • MGC14797 antibody
    • OTTHUMP00000024063 antibody
    • PHD finger protein 6 antibody
    • PHD like zinc finger protein antibody
    • PHD-like zinc finger protein antibody
    • Phf6 antibody
    • PHF6_HUMAN antibody
    see all

Anti-PHD finger protein 6 antibody 图像

  • Anti-PHD finger protein 6 antibody (ab111844) at 1/1000 dilution + MCF 7 whole cell lysate at 30 µg

    Predicted band size : 35 kDa
  • ab111844 at 1/500 dilution staining PHD finger protein 6 in Paraformaldehyde-fixed MCF7 cells by Immunofluorescence. Lower image shows cells co-stained with Hoechst 33342.

Anti-PHD finger protein 6 antibody (ab111844)参考文献

ab111844 has not yet been referenced specifically in any publications.

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