• 产品名称
  • 描述
    兔多克隆抗体to PHAP1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to amino acids 149-163 of Human I1 alpha PP2A.



Our Abpromise guarantee covers the use of ab1181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
  • 应用说明
    Reactive with I1aPP2A from diverse tissue sources by Western blotting. Used at 1:100 with cell extracts.
    Other immunodetection procedures not tested.
  • 靶标

    • 功能
      Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.
    • 组织特异性
      Expressed in all tissues tested. Highly expressed in kidney and skeletal muscle, moderate levels of expression in brain, placenta and pancreas, and weakly expressed in lung. Found in all regions of the brain examined (amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus), with highest levels in amygdala.
    • 序列相似性
      Belongs to the ANP32 family.
      Contains 4 LRR (leucine-rich) repeats.
      Contains 1 LRRCT domain.
    • 翻译后修饰
      Phosphorylated on serine residues.
      The N-terminus is blocked.
      Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group.
    • 细胞定位
      Nucleus. Cytoplasm. Endoplasmic reticulum. Translocates to the cytoplasm during the process of neuritogenesis (By similarity). Shuttles between nucleus and cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • acidic (leucine-rich) nuclear phosphoprotein 32 family, member A antibody
      • Acidic leucine-rich nuclear phosphoprotein 32 family member A antibody
      • Acidic nuclear phosphoprotein 32 family member A antibody
      • Acidic nuclear phosphoprotein pp32 antibody
      • AN32A_HUMAN antibody
      • ANP32A antibody
      • C15orf1 antibody
      • Cerebellar leucine rich acidic nuclear protein antibody
      • Hepatopoietin Cn antibody
      • HPPCn antibody
      • I1PP2A antibody
      • Inhibitor 1 of protein phosphatase 2A antibody
      • inhibitor-1 of protein phosphatase-2A antibody
      • Lanp antibody
      • Leucine rich acidic nuclear protein antibody
      • Leucine-rich acidic nuclear protein antibody
      • MAPM antibody
      • Mapmodulin antibody
      • MGC119787 antibody
      • MGC150373 antibody
      • PHAPI antibody
      • Potent heat stable protein phosphatase 2A inhibitor I1PP2A antibody
      • Potent heat-stable protein phosphatase 2A inhibitor I1PP2A antibody
      • PP32 antibody
      • Putative HLA DR associated protein I antibody
      • Putative HLA-DR-associated protein I antibody
      • Putative human HLA class II associated protein I antibody
      • Putative human HLA class II-associated protein antibody
      see all

    Anti-PHAP1 antibody 图像

    • Western blot of 10 µg HEK 293 cell extracts with Anti- I1α (GLO149). The band corresponds to I1αPP2A (~ 30 kDa).


    Anti-PHAP1 antibody (ab1181)参考文献

    ab1181 has not yet been referenced specifically in any publications.

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