概述

  • 产品名称Anti-PHAP抗体
    参阅全部 PHAP 一抗
  • 描述
    兔多克隆抗体to PHAP
  • 特异性This antibody cross-reacts with both PHAP I and PHAP III.
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (Human).

  • 阳性对照
    • Raji whole cell lysate.
  • 常规说明Stable for one year.

性能

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应用

Our Abpromise guarantee covers the use of ab5987 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
ICC/IF
  • 应用说明IHC-P: Use at a concentration of 10 µg/ml.
    WB: Use at a concentration of 0.5 - 2.0 µg/ml. Detects bands of approximately 35 and 32 kDa corresponding to PHAPIII and PHAPI respectively. Two cross reacting bands are also observed below 32 kDa, which may be differentially spliced forms of PHAPI.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性This antibody recognizes all three identified isoforms of human, mouse and rat PHAP, including PHAP I, PHAP I2a, and PHAP III. The PHAP proteins(tumor suppressor putative HLA-DR associated proteins) are important regulators of mitochondrial apoptosis. PHAP facilitates apoptosome-mediated caspase-9 activation to stimulate the mitochondrial apoptosis pathway. In addition, PHAP opposes both Ras- and myc- mediated cell transformation.
    • 细胞定位Nuclear
    • 数据库链接
    • 别名
      • Acidic (leucine-rich) nuclear phosphoprotein 32 family, member B antibody
      • Acidic leucine-rich nuclear phosphoprotein 32 family member A antibody
      • Acidic nuclear phosphoprotein pp32 antibody
      • ANP32A antibody
      • ANP32B antibody
      • I1PP2A antibody
      • LANP antibody
      • MAPM antibody
      • PHAP1 antibody
      • PHAPI2 antibody
      • PHAPIII antibody
      • PP32 antibody
      • Putative Human HLA Class II Associated Protein antibody
      see all

    Anti-PHAP antibody 图像

    • Immunofluorescence of PHAP in Human small intestine tissue with ab5987 at 20 ug/mL.



    • Predicted band size : 29 kDa

      Western blot analysis of PHAP expression in human Raji cell llysate with anti-PHAP at 1 µg/ml. The two bands below PHAP I might be differently spliced isoforms of PHAP.

      Western blot analysis of PHAP expression in human Raji cell llysate with anti-PHAP at 1 µg/ml. The two bands below PHAP I might be differently spliced isoforms of PHAP.
    • ab5987 at 10µg/ml staining PHAP in human small intestine tissue by IHC 

    Anti-PHAP antibody (ab5987)参考文献

    ab5987 has not yet been referenced specifically in any publications.

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