概述

  • 产品名称Anti-PGRPS抗体
    参阅全部 PGRPS 一抗
  • 描述
    山羊多克隆抗体to PGRPS
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog
  • 免疫原

    Synthetic peptide:

    PGNQLYHLIQN

    by a Cysteine residue linker, corresponding to C terminal amino acids 179-189 of Human PGRPS (NP_005082.1).

  • 阳性对照
    • Human spleen tissue; Jurkat cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab113625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 22 kDa). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Lu et al, J Biol Chem. 2006 Mar 3;281(9):5895-907; PMID: 16354652).
IHC-P Use a concentration of 3.75 µg/ml.

靶标

  • 功能Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
  • 组织特异性Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.
  • 序列相似性Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
  • 翻译后修饰N-glycosylated. N-glycosylation is required for bactericidal activity.
  • 细胞定位Secreted. Cytoplasmic granule.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MGC126894 antibody
    • MGC126896 antibody
    • Peptidoglycan recognition protein 1 antibody
    • Peptidoglycan recognition protein antibody
    • Peptidoglycan recognition protein short antibody
    • PGLYRP antibody
    • PGLYRP1 antibody
    • PGRP antibody
    • PGRP S antibody
    • PGRP-S antibody
    • PGRP1_HUMAN antibody
    • PHRP, short antibody
    • SBBI68 antibody
    • TAG7 antibody
    • TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein) antibody
    • TNFSF 3L antibody
    • TNFSF3L antibody
    • UNQ639/PRO1269 antibody
    see all

Anti-PGRPS antibody 图像

  • Anti-PGRPS antibody (ab113625) at 0.3 µg/ml + Jurkat cell lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 22 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)
  • ab113625 at 3.75ug/ml staining PGRPS in Formalin-fixed, Paraffin-embedded Human spleen tissue by Immunohistochemistry.

Anti-PGRPS antibody (ab113625)参考文献

ab113625 has not yet been referenced specifically in any publications.

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