Anti-PGRPS抗体[188C424] (ab13903)


  • 产品名称Anti-PGRPS抗体[188C424]
    参阅全部 PGRPS 一抗
  • 描述
    小鼠单克隆抗体[188C424] to PGRPS
  • 经测试应用适用于: ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide: YVLKGHRDVQRTLSPG , corresponding to amino acids 165-180 of Human PGRPS.

  • 阳性对照
    • Tested with mouse spleen tissue.



Our Abpromise guarantee covers the use of ab13903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
  • 应用说明WB: Use at a concentration of 2 µg/ml. Predicted molecular weight: 22 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
    • 组织特异性Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.
    • 序列相似性Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
    • 翻译后修饰N-glycosylated. N-glycosylation is required for bactericidal activity.
    • 细胞定位Secreted. Cytoplasmic granule.
    • Information by UniProt
    • 数据库链接
    • 别名
      • MGC126894 antibody
      • MGC126896 antibody
      • Peptidoglycan recognition protein 1 antibody
      • Peptidoglycan recognition protein antibody
      • Peptidoglycan recognition protein short antibody
      • PGLYRP antibody
      • PGLYRP1 antibody
      • PGRP antibody
      • PGRP S antibody
      • PGRP-S antibody
      • PGRP1_HUMAN antibody
      • PHRP, short antibody
      • SBBI68 antibody
      • TAG7 antibody
      • TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein) antibody
      • TNFSF 3L antibody
      • TNFSF3L antibody
      • UNQ639/PRO1269 antibody
      see all

    Anti-PGRPS antibody [188C424] 图像

    • ab13903 at 1/100 staining human bone Marrow derived CD34+ cells by ICC/IF. The cells were paraformaldehyde fixed, permeabilized and blocked with BSA before incubation with the antibody for 24 hours at 4°C. A FITC conjugated goat anti-mouse IgG was used as the secondary. The cells were counterstained with DAPI.

      The image shows staining mainly in the cytoplasmic region.

      See Abreview

    • Anti-PGRPS antibody [188C424] (ab13903) at 2 µg/ml + Jurkat cell lysate

      Predicted band size : 22 kDa
      Observed band size : 28 kDa (why is the actual band size different from the predicted?)

    Anti-PGRPS antibody [188C424] (ab13903)参考文献

    ab13903 has not yet been referenced specifically in any publications.

    Product Wall

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Immunocytochemistry/ Immunofluorescence
    Sample Human Cell (Bone Marrow derived CD34+ cells)
    Specification Bone Marrow derived CD34+ cells
    Fixative Paraformaldehyde
    Permeabilization Yes - 0.25% Triton X-100 for 10min
    Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 3% · Temperature: 20°C

    Abcam user community

    Verified customer

    提交于 Jun 29 2007

    Thank you for your enquiry. Unfortunately I do not have access to the Lui paper. According to the Swiss Prot reference for mouse the target is “strongly expressed in spleen”, this was the positive control that was used. The predicted molecular weig...

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    Thank you for your enquiry. This product will cross react with mouse, the data sheet has now been updated t reflect this. Western blot analysis was carried out on PGRP-S in tissue lysates from mouse spleen using Ab13903 at a dilution of 2 µg/ml. Thank ...

    Read More