The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution.
1/2000. Predicted molecular weight: 62 kDa.
Peptidoglycan recognition proteins (PGRPs) are pattern recognition molecules that recognize bacteria and their unique cell wall component, peptidoglycan(PGN).Mammals have four PGRPs, designated in humans PGRP-S(24kDa), PGRP-L(60~65kDa), PGRP-Ia(38kDa), and PGRP-Iß(44kDa). Human PGRPsare differentially expressed in various tissues and organs: PGRP-S mainly in the bone marrow and Polymorphonuclearleukocyte (PMNs), PGRP-L mainly in the liver, and PGRP-Iaand PGRP-Ibmainly in the esophagus.The function of only one mammalian PGRP, PGRP-S, is currently known. Mouse PGRP-S is present in neutrophilsand inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophilantibacterial protein.