概述

  • 产品名称Anti-PGEA1抗体
    参阅全部 PGEA1 一抗
  • 描述
    小鼠单克隆抗体to PGEA1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 18-127 of Human PGEA1

性能

应用

Our Abpromise guarantee covers the use of ab57020 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Inhibits the Wnt/Wingless pathway by binding to beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
    • 组织特异性Widely expressed. Expressed at higher levels in heart, skeletal muscle, kidney and placenta. Also found in brain, lung, liver and testis. Significantly down-regulated in thyroid and metastatic uterine tumors.
    • 序列相似性Belongs to the chibby family.
    • 细胞定位Nucleus speckle. Golgi apparatus, trans-Golgi network. Nuclear, in a punctate manner. Also found in the trans-Golgi.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ARPP-binding protein antibody
      • C22orf2 antibody
      • CBY antibody
      • Cby1 antibody
      • CBY1_HUMAN antibody
      • Cytosolic leucine rich protein antibody
      • Cytosolic leucine-rich protein antibody
      • Golgi and endoplasmic reticulum-associated 1 antibody
      • HRIHFB2025 antibody
      • PIGEA 14 antibody
      • PIGEA-14 antibody
      • PKD2 interactor antibody
      • PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 antibody
      • Protein Chibby antibody
      • Protein chibby homolog 1 antibody
      see all

    Anti-PGEA1 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57020 PGEA1 antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa

    Anti-PGEA1 antibody (ab57020)参考文献

    ab57020 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"