概述

  • 产品名称Anti-PEX13抗体
    参阅全部 PEX13 一抗
  • 描述
    兔多克隆抗体to PEX13
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to a sequence within amino acids 342 - 403 of Human PEX13.

  • 阳性对照
    • MOLT4 whole cell lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab96841 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 44 kDa.

靶标

  • 功能Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins.
  • 疾病相关Defects in PEX13 are the cause of peroxisome biogenesis disorder complementation group 13 (PBD-CG13) [MIM:601789]; also known as PBD-CGH. PBD-CG13 is a peroxisomal disorder arising from a failure of protein import into the peroxisomal membrane or matrix. The peroxisome biogenesis disorders (PBD group) are genetically heterogeneous with at least 14 distinct genetic groups as concluded from complementation studies. Include disorders are: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlapping phenotypes known as the Zellweger spectrum (PBD-ZSS).
    Defects in PEX13 are a cause of adrenoleukodystrophy neonatal (NALD) [MIM:202370]. NALD is a peroxisome biogenesis disorder (PBD) characterized by the accumulation of very long-chain fatty acids, adrenal insufficiency and mental retardation.
  • 序列相似性Belongs to the peroxin-13 family.
    Contains 1 SH3 domain.
  • 细胞定位Peroxisome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2610008O20Rik antibody
    • NALD antibody
    • OTTMUSP00000005454 antibody
    • Peroxin 13 antibody
    • Peroxin-13 antibody
    • Peroxin13 antibody
    • Peroxisomal membrane protein PEX 13 antibody
    • Peroxisomal membrane protein PEX13 antibody
    • Peroxisome biogenesis factor 13 antibody
    • PEX 13 antibody
    • pex13 antibody
    • PEX13_HUMAN antibody
    • RP23-188K3.1 antibody
    • ZWS antibody
    see all

Anti-PEX13 antibody 图像

  • Anti-PEX13 antibody (ab96841) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg

    Predicted band size : 44 kDa

Anti-PEX13 antibody (ab96841)参考文献

ab96841 has not yet been referenced specifically in any publications.

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