Anti-Pet1抗体(ab108265)

概述

  • 产品名称Anti-Pet1抗体
    参阅全部 Pet1 一抗
  • 描述
    兔多克隆抗体to Pet1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Chicken, Guinea pig, Cow, Drosophila melanogaster
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (PLSPAVQKGSGQIQLWQFLLELLADRANAGCIAWEGGHGEFKLTDPDEV A) of Human Pet1 (NP_059991).

  • 阳性对照
    • HeLa cell line lysate

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab108265 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Functions as a transcriptional regulator. According to PubMed:12761502, it functions as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth.
  • 组织特异性In brain, exclusively expressed in the major serotonergic neurons of the dorsal and median raphe nuclei located in the midbrain and pons. Also detected in prostate and small intestine.
  • 疾病相关Genetic variation in FEV may be associated with susceptibility to sudden infant death syndrome (SIDS) [MIM:272120]. SIDS remains elusive in its causes and devastating in its consequences. Despite the impressive decline in the incidence of SIDS since the recommendation to avoid the prone sleep position, SIDS remains a leading cause of death in the first year of life.
    Note=A chromosomal aberration involving FEV is found in Ewing tumors. Translocation t(2;21;22)(q23;q22;q12) that forms a EWSR1-FEV fusion protein with a potential oncogenic activity.
  • 序列相似性Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ETS-domain transcription factor antibody
    • FEV (ETS oncogene family) antibody
    • FEV antibody
    • FEV_HUMAN antibody
    • Fifth Ewing sarcoma variant antibody
    • Fifth Ewing variant protein antibody
    • HSRNAFEV antibody
    • mPet1 antibody
    • PC12 ETS domain-containing transcription factor 1 antibody
    • PC12 ETS factor 1 antibody
    • Pet-1 antibody
    • Protein FEV antibody
    see all

Anti-Pet1 antibody 图像

  • Anti-Pet1 antibody (ab108265) at 1 µg/ml + HeLa cell line lysate at 10 µg

    Predicted band size : 25 kDa

Anti-Pet1 antibody (ab108265)参考文献

ab108265 has not yet been referenced specifically in any publications.

Product Wall

Thank you very much for your interest in ab108265 Anti-PET 1 antibody. To our knowledge this product has not been tested in rat. However a BLAST of the immunogen used showed 100% identity with rat. NP_653354.2Score = 106 bits (265), Expect = 3e-27,...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"