概述

  • 产品名称Anti-Pescadillo抗体
    参阅全部 Pescadillo 一抗
  • 描述
    兔多克隆抗体to Pescadillo
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residues 535 and the C-terminus (residue 588) of Human Pescadillo (NP_055118.1).

  • 阳性对照
    • Human breast adenocarcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab84512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
    • 组织特异性Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin.
    • 序列相似性Belongs to the pescadillo family.
      Contains 1 BRCT domain.
    • 翻译后修饰Sumoylated.
    • 细胞定位Nucleus > nucleolus. Nucleus > nucleoplasm. Chromosome. Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ43790 antibody
      • Homo sapiens pescadillo mRNA complete cds antibody
      • PES antibody
      • PES 1 antibody
      • pes1 antibody
      • PESC_HUMAN antibody
      • Pescadillo (zebrafish) homolog 1 containing BRCT domain antibody
      • Pescadillo homolog 1 antibody
      • Pescadillo homolog 1 containing BRCT domain (zebrafish) antibody
      • Pescadillo homolog antibody
      • Pescadillo ribosomal biogenesis factor 1 antibody
      see all

    Anti-Pescadillo antibody 图像

    • ab84512, at 1/250 dilution, staining Pescadillo in formalin-fixed, paraffin-embedded human breast adenocarcinoma by Immunohistochemistry, using DAB staining.

    Anti-Pescadillo antibody (ab84512)参考文献

    ab84512 has not yet been referenced specifically in any publications.

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