概述

  • 产品名称Anti-Pescadillo抗体
    参阅全部 Pescadillo 一抗
  • 描述
    兔多克隆抗体to Pescadillo
  • 经测试应用适用于: IHC-P, IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
  • 免疫原

    Synthetic peptide corresponding to a region between residues 25 and 75 of human Pescadillo (NP_055118.1)

  • 阳性对照
    • HeLa whole cell lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab72537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/1000 - 1/5000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IP Use at 2-5 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
    • 组织特异性Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin.
    • 序列相似性Belongs to the pescadillo family.
      Contains 1 BRCT domain.
    • 翻译后修饰Sumoylated.
    • 细胞定位Nucleus > nucleolus. Nucleus > nucleoplasm. Chromosome. Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ43790 antibody
      • Homo sapiens pescadillo mRNA complete cds antibody
      • PES antibody
      • PES 1 antibody
      • pes1 antibody
      • PESC_HUMAN antibody
      • Pescadillo (zebrafish) homolog 1 containing BRCT domain antibody
      • Pescadillo homolog 1 antibody
      • Pescadillo homolog 1 containing BRCT domain (zebrafish) antibody
      • Pescadillo homolog antibody
      • Pescadillo ribosomal biogenesis factor 1 antibody
      see all

    Anti-Pescadillo antibody 图像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon carcinoma (left) and ovarian carcinoma (right) tissues labelling Pescadillo with ab72537 at 1/1000 (1 µg/ml). Detection: DAB.

    Anti-Pescadillo antibody (ab72537)参考文献

    ab72537 has not yet been referenced specifically in any publications.

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