Anti-Persephin抗体(Biotin) (ab83410)

概述

  • 产品名称Anti-Persephin抗体(Biotin)
    参阅全部 Persephin 一抗
  • 描述
    兔多克隆抗体to Persephin (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: ELISA, Sandwich ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Highly pure (>98%) recombinant human Persephin

性能

  • 形式Lyophilised:Centrifuge vial prior to opening. Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯化说明ab83410 is affinity purified and sterile filtered.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab83410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant human Persephin.
Sandwich ELISA Use a concentration of 0.25 - 1 µg/ml. When used as detection antibody with recommended pair, allows the detection of at least 0.2 - 0.4 ng/well of recombinant human Persephin.
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 17 kDa. The detection limit for recombinant human Persephin is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

靶标

  • 相关性Persephin is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. Persephin has a similar structure to other family members, glial cell line-derived neurotrophic factor, Artemin and neurturin. All these proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Persephin signals through a multicomponent receptor system, composed of RET and one of four GFR alpha (alpha1-alpha4) receptors. The GFRalpha4 was first identified in chicken and was later shown to be the preferential binding subunit for Persephin. In contrast to GDNF and Neurturin, Persephin does not support survival of peripheral neurons.
  • 细胞定位Secreted
  • 数据库链接
  • 别名
    • Persephin antibody
    • PSP antibody
    • PSPN antibody

Anti-Persephin antibody (Biotin) (ab83410)参考文献

ab83410 has not yet been referenced specifically in any publications.

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