Anti-Peroxiredoxin 1抗体(ab79284)

概述

  • 产品名称Anti-Peroxiredoxin 1抗体
    参阅全部 Peroxiredoxin 1 一抗
  • 描述
    山羊多克隆抗体to Peroxiredoxin 1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Cynomolgus Monkey, Chinese Hamster
  • 免疫原

    Synthetic peptide:

    C-SDPKRTIAQDYG

    , corresponding to internal sequence amino acids 106-117 of Human Peroxiredoxin 1 (NP_859048.1)

  • 阳性对照
    • HEK293, A431 and HepG2 cell lysates.
  • 常规说明


    Reported variants represent identical proteins: NP_002565.1, NP_859047.1, NP_859048.1.

性能

应用

Our Abpromise guarantee covers the use of ab79284 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 24 kDa (predicted molecular weight: 22 kDa).

靶标

  • 功能Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.
  • 序列相似性Belongs to the ahpC/TSA family.
    Contains 1 thioredoxin domain.
  • 翻译后修饰Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity.
  • 细胞定位Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Heme binding 23 kDa protein antibody
    • MSP23 antibody
    • Natural killer cell-enhancing factor A antibody
    • NKEF A antibody
    • NKEF-A antibody
    • NKEFA antibody
    • OSF3 antibody
    • Osteoblast specific factor 3 antibody
    • PAG antibody
    • Paga antibody
    • PAGB antibody
    • Peroxiredoxin-1 antibody
    • PRDX1 antibody
    • PRDX1_HUMAN antibody
    • Proliferation associated gene A antibody
    • Proliferation-associated gene protein antibody
    • PRX1 antibody
    • PrxI antibody
    • TDPX2 antibody
    • Thioredoxin peroxidase 2 antibody
    • Thioredoxin-dependent peroxide reductase 2 antibody
    see all

Anti-Peroxiredoxin 1 antibody 图像

Anti-Peroxiredoxin 1 antibody (ab79284)参考文献

ab79284 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab79284.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"