概述

  • 产品名称Anti-Perilipin A抗体
    参阅全部 Perilipin A 一抗
  • 描述
    山羊多克隆抗体to Perilipin A
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Pig, Chimpanzee, Rhesus monkey
  • 免疫原

    Synthetic peptide:

    C-PREKPKRRVSDS

    , corresponding to iamino acids 488-499 of Human Perilipin

  • 阳性对照
    • Human Adipose tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab60269 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.01 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 56 kDa).
ICC/IF Use at an assay dependent dilution. PubMed: 20335253

靶标

  • 功能Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness.
  • 组织特异性Adipocytes.
  • 序列相似性Belongs to the perilipin family.
  • 翻译后修饰Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet.
  • 细胞定位Lipid droplet. Lipid droplet surface-associated.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Lipid droplet associated protein antibody
    • Lipid droplet-associated protein antibody
    • PERI antibody
    • Perilipin antibody
    • Perilipin-1 antibody
    • PerilipinA antibody
    • PLIN antibody
    • PLIN1 antibody
    • PLIN1_HUMAN antibody
    see all

Anti-Perilipin A antibody 图像

Anti-Perilipin A antibody (ab60269)参考文献

This product has been referenced in:
  • Cheung W  et al. Rotaviruses associate with cellular lipid droplet components to replicate in viroplasms, and compounds disrupting or blocking lipid droplets inhibit viroplasm formation and viral replication. J Virol 84:6782-98 (2010). ICC/IF ; Rhesus monkey . Read more (PubMed: 20335253) »

See 1 Publication for this product

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