概述

描述

  • 性质
    Synthetic

相关产品

技术指标

Our Abpromise guarantee covers the use of ab5009 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • 补充说明

    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat perilipin-1, catalog ab3526. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • Lipid droplet associated protein
    • Lipid droplet-associated protein
    • PERI
    • Perilipin
    • Perilipin A
    • Perilipin-1
    • PerilipinA
    • PLIN
    • PLIN1
    • PLIN1_HUMAN
    see all
  • 功能
    Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness.
  • 组织特异性
    Adipocytes.
  • 序列相似性
    Belongs to the perilipin family.
  • 翻译后修饰
    Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet.
  • 细胞定位
    Lipid droplet. Lipid droplet surface-associated.
  • Information by UniProt

文献

This product has been referenced in:
  • Linden JR  et al. Clostridium perfringens Epsilon Toxin Causes Selective Death of Mature Oligodendrocytes and Central Nervous System Demyelination. MBio 6:e02513 (2015). IHC-P, ICC, IHC - Wholemount ; Mouse . Read more (PubMed: 26081637) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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