Anti-Pericentrin抗体(ab84542)

概述

  • 产品名称Anti-Pericentrin抗体
    参阅全部 Pericentrin 一抗
  • 描述
    兔多克隆抗体to Pericentrin
  • 经测试应用适用于: ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to a region between residues 175 and 225 of Human Pericentrin (NP_006022.3)

  • 阳性对照
    • HeLa Cells.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab84542 was affinity purified using an epitope specific to Pericentrin immobilized on solid support.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF
  • 应用说明ICC/IF: 1/100 - 1/500. Formaldehyde-Fixed and acetone-fixed cells.
    Permeabilization with Triton-X 100 is recommended.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome.
    • 组织特异性Expressed in all tissues tested, including placenta, liver, kidney and thymus.
    • 疾病相关Microcephalic osteodysplastic primordial dwarfism 2
    • 结构域Composed of a coiled-coil central region flanked by non-helical N- and C-terminals.
    • 细胞定位Cytoplasm > cytoskeleton > microtubule organizing center > centrosome. Centrosomal at all stages of the cell cycle. Remains associated with centrosomes following microtubule depolymerization. Colocalized with DISC1 at the centrosome.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Centrosome Marker antibody
      • Ken antibody
      • Kendrin antibody
      • KIAA0402 antibody
      • MOPD2 antibody
      • PCN antibody
      • PCNT 2 antibody
      • PCNT antibody
      • PCNT B antibody
      • PCNT_HUMAN antibody
      • PCNT1 antibody
      • PCNT2 antibody
      • PCNTB antibody
      • PCTN2 antibody
      • Pericentrin 1 antibody
      • Pericentrin 2 antibody
      • Pericentrin 380 antibody
      • Pericentrin antibody
      • Pericentrin B antibody
      • Pericentrin-B antibody
      • SCKL4 antibody
      see all

    Anti-Pericentrin antibody 图像

    • ab84542 at 1/100 dilution staining Pericentrin in HeLa cells by Immunofluorescence, NBF-fixed. Detection: Red-fluorescent Alexa Fluor 594 goat antirabbit IgG.
    • ab84542 at 1/500 dilution staining Pericentrin in asynchronous HeLa cells by Immunofluorescence, NBF-fixed. Detection: Red-fluorescent Alexa Fluor 594 goat antirabbit IgG.
    • ab84542 at 1/500 dilution staining Pericentrin in asynchronous HeLa cells by Immunofluorescence, NBF-fixed. Detection: Red-fluorescent Alexa Fluor 594 goat antirabbit IgG.
    • ab84542 at 1/100 dilution staining Pericentrin in asynchronous HeLa cells by Immunofluorescence, Acetone-fixed. Detection: Red-fluorescent Alexa Fluor 594 goat antirabbit IgG.

    Anti-Pericentrin antibody (ab84542)参考文献

    ab84542 has not yet been referenced specifically in any publications.

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