概述

  • 产品名称
  • 描述
    小鼠多克隆抗体to PELO
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    PELO full-length human protein (AAH05889.1, aa 1-385)

  • 阳性对照
    • Human stomach lysate, Hela cell lysate and PELO transfected 293T cell lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab88673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa.

靶标

  • 功能
    Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity.
  • 组织特异性
    Ubiquitously expressed.
  • 序列相似性
    Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
  • 结构域
    The N-terminal domain has the RNA-binding Sm fold. It may harbor the endoribonuclease activity.
  • 细胞定位
    Nucleus. Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CGI 17 antibody
    • CGI17 antibody
    • pelo antibody
    • PELO_HUMAN antibody
    • pelota (Drosophila) homolog antibody
    • pelota homolog antibody
    • PRO1770 antibody
    • Protein pelota homolog antibody
    see all

图片

  • Anti-PELO antibody (ab88673) at 1 µg/ml + Human stomach lysate at 50 µg

    Predicted band size : 43 kDa
    Observed band size : 43 kDa
  • Anti-PELO antibody (ab88673) at 1 µg/ml + Hela cell lysate at 50 µg

    Predicted band size : 43 kDa
    Observed band size : 43 kDa
  • All lanes : Anti-PELO antibody (ab88673) at 1 µg/ml

    Lane 1 : PELO transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 43 kDa
    Observed band size : 43 kDa

实验方案

文献

ab88673 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab88673.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册