Anti-PDSS2抗体[4F9] (ab119804)

概述

  • 产品名称Anti-PDSS2抗体[4F9]
    参阅全部 PDSS2 一抗
  • 描述
    小鼠单克隆抗体[4F9] to PDSS2
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein of Human PDSS2 produced in HEK293T cells (NP_065114).

  • 阳性对照
    • HEK293T cells transfected with PDSS2, Adenocarcinoma of Human ovary tissue, COS7 cells transiently transfected with PDSS2
  • 常规说明Dilute in PBS (pH7.3) before use.

性能

应用

Our Abpromise guarantee covers the use of ab119804 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000. Predicted molecular weight: 44 kDa.
IHC-P 1/150.
ICC/IF 1/100.

靶标

  • 功能Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10.
  • 通路Cofactor biosynthesis; ubiquinone biosynthesis.
  • 疾病相关Defects in PDSS2 are a cause of coenzyme Q10 deficiency (COQ10D) [MIM:607426]. Coenzyme Q10 deficiency is an autosomal recessive disorder with variable manifestations. It can be associated with three main clinical phenotypes: a predominantly myopathic form with central nervous system involvement, an infantile encephalomyopathy with renal dysfunction and an ataxic form with cerebellar atrophy.
  • 序列相似性Belongs to the FPP/GGPP synthase family.
  • 细胞定位Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • All-trans-decaprenyl-diphosphate synthase subunit 2 antibody
    • bA59I9.3 antibody
    • C6orf210 antibody
    • Candidate tumor suppressor protein antibody
    • chromosome 6 open reading frame 210 antibody
    • Decaprenyl pyrophosphate synthase subunit 2 antibody
    • decaprenyl pyrophosphate synthetase subunit 2 antibody
    • Decaprenyl-diphosphate synthase subunit 2 antibody
    • DLP1 antibody
    • DLP1_HUMAN antibody
    • hDLP1 antibody
    • Pdss2 antibody
    • prenyl (decaprenyl) diphosphate synthase, subunit 2 antibody
    • subunit 2 of decaprenyl diphosphate synthase antibody
    see all

Anti-PDSS2 antibody [4F9] 图像

  • All lanes : Anti-PDSS2 antibody [4F9] (ab119804) at 1/2000 dilution

    Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control
    Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY PDSS2

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 44 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC207892)
  • Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using ab119804 at a dilution of 1/150.
  • Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDSS2 using ab119804 at a dilution of 1/100.

Anti-PDSS2 antibody [4F9] (ab119804)参考文献

ab119804 has not yet been referenced specifically in any publications.

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