概述

  • 产品名称Anti-PDLIM5抗体
    参阅全部 PDLIM5 一抗
  • 描述
    兔多克隆抗体to PDLIM5
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Xenopus laevis, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
  • 免疫原

    Synthetic peptide dessigned within residues: EAGDM FLEA LGYTWH DTC FVCSVCC ES LEGQTFFS K KDKPLCKKH AHSVNF, corresponding to C terminal amino acids 546-596 of Human PDLIM5 (NP_006448.2)

  • 阳性对照
    • HeLa whole cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab85967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000 - 1/10000. Predicted molecular weight: 64 kDa.
IP Use at 2-5 µg/mg of lysate.

靶标

  • 功能May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses.
  • 组织特异性Heart and skeletal muscle specific. Expression is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression.
  • 序列相似性Contains 3 LIM zinc-binding domains.
    Contains 1 PDZ (DHR) domain.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse > synaptosome. Cytoplasm. Detected both at presynaptic and postsynaptic sites.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ENH antibody
    • ENH1 antibody
    • Enigma homolog antibody
    • Enigma like LIM domain protein antibody
    • Enigma like PDZ and LIM domains protein antibody
    • Enigma-like PDZ and LIM domains protein antibody
    • L 9 antibody
    • L9 antibody
    • LIM antibody
    • PDLI5_HUMAN antibody
    • PDLIM5 antibody
    • PDZ and LIM domain 5 antibody
    • PDZ and LIM domain protein 5 antibody
    see all

Anti-PDLIM5 antibody 图像

  • All lanes : Anti-PDLIM5 antibody (ab85967) at 0.04 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg


    Predicted band size : 64 kDa


    Exposure time : 30 seconds
  • 1mg HeLa whole cell lysate was immunoprecipitated using ab85967 at 3µg. 20% of IP was loaded/lane and PDLIM5 was detected with ab85967 at 1µg/ml (lane 1) or a control IgG (lane 2).
    Detection: chemiluminescence with exposure time of 10 seconds.

Anti-PDLIM5 antibody (ab85967)参考文献

ab85967 has not yet been referenced specifically in any publications.

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