概述

  • 产品名称Anti-PDLIM5抗体
    参阅全部 PDLIM5 一抗
  • 描述
    兔多克隆抗体to PDLIM5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 2 - 51 (SNYSVSLVGP APWGFRLQGG KDFNMPLTIS SLKDGGKAAQ ANVRIGDVVL) of human PDLIM5 (NP_006448).

  • 阳性对照
    • HepG2 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab83060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses.
  • 组织特异性Heart and skeletal muscle specific. Expression is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression.
  • 序列相似性Contains 3 LIM zinc-binding domains.
    Contains 1 PDZ (DHR) domain.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse > synaptosome. Cytoplasm. Detected both at presynaptic and postsynaptic sites.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ENH antibody
    • ENH1 antibody
    • Enigma homolog antibody
    • Enigma like LIM domain protein antibody
    • Enigma like PDZ and LIM domains protein antibody
    • Enigma-like PDZ and LIM domains protein antibody
    • L 9 antibody
    • L9 antibody
    • LIM antibody
    • PDLI5_HUMAN antibody
    • PDLIM5 antibody
    • PDZ and LIM domain 5 antibody
    • PDZ and LIM domain protein 5 antibody
    see all

Anti-PDLIM5 antibody 图像



  • Predicted band size : 64 kDa
    Western blot analysis of Human fetal lung tissue lysate labeling PDLIM5 with ab83060 at 1.0µg/ml.


  • Predicted band size : 64 kDa
    Western blot analysis of Human fetal liver tissue lysate labeling PDLIM5 with ab83060 at 1.0µg/ml.


  • Predicted band size : 64 kDa
    Western blot analysis of Human fetal heart tissue lysate labeling PDLIM5 with ab83060 at 1.0µg/ml.


  • Predicted band size : 64 kDa
    Western blot analysis of Human fetal brain tissue lysate labeling PDLIM5 with ab83060 at 1.0µg/ml.


  • Predicted band size : 64 kDa
    Western blot analysis of Human adult placenta tissue lysate labeling PDLIM5 with ab83060 at 1.0µg/ml.
  • Anti-PDLIM5 antibody (ab83060) at 1 µg/ml (in 5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 64 kDa
    Observed band size : 64 kDa
  • All lanes : Anti-PDLIM5 antibody (ab83060) at 1 µg/ml

    Lane 1 : HepG2
    Lane 2 : HepG2 with blocking peptide at 5 µg/ml

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 64 kDa

Anti-PDLIM5 antibody (ab83060)参考文献

ab83060 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab83060.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"