概述

  • 产品名称Anti-PDLIM2抗体
    参阅全部 PDLIM2 一抗
  • 描述
    小鼠多克隆抗体to PDLIM2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length PDLIM2 protein (Human)

  • 阳性对照
    • PDLIM2 transfected 293T cell lysate and human liver tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab68220 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 36, 38 kDa (predicted molecular weight: 37 kDa).

靶标

  • 功能Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity.
  • 序列相似性Contains 1 LIM zinc-binding domain.
    Contains 1 PDZ (DHR) domain.
  • 细胞定位Cytoplasm > cytoskeleton; Nucleus; Cytoplasm. Nucleus. May be partially nuclear and Cytoplasm > cytoskeleton. Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ34715 antibody
    • MYSTIQUE antibody
    • OTTHUMP00000162522 antibody
    • OTTHUMP00000205197 antibody
    • OTTHUMP00000205198 antibody
    • OTTHUMP00000205199 antibody
    • OTTHUMP00000205200 antibody
    • OTTHUMP00000205202 antibody
    • OTTHUMP00000205203 antibody
    • PDLI2_HUMAN antibody
    • Pdlim2 antibody
    • PDZ and LIM domain 2 (mystique) antibody
    • PDZ and LIM domain protein 2 antibody
    • PDZ-LIM protein mystique antibody
    • SLIM antibody
    • Stat-interacting LIM protein antibody
    see all

Anti-PDLIM2 antibody 图像

  • Anti-PDLIM2 antibody (ab68220) at 1/500 dilution + human liver tissue lysate at 25 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 37 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-PDLIM2 antibody (ab68220) at 1/500 dilution

    Lane 1 : PDLIM2 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 37 kDa
    Observed band size : 36 kDa (why is the actual band size different from the predicted?)

Anti-PDLIM2 antibody (ab68220)参考文献

This product has been referenced in:
  • Vanoirbeek E  et al. PDLIM2 expression is driven by vitamin D and is involved in the pro-adhesion, and anti-migration and -invasion activity of vitamin D. Oncogene N/A:N/A (2013). Human . Read more (PubMed: 23584482) »

See 1 Publication for this product

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