Anti-PDLIM2抗体[10C4] (ab119243)

概述

  • 产品名称Anti-PDLIM2抗体[10C4]
    参阅全部 PDLIM2 一抗
  • 描述
    小鼠单克隆抗体[10C4] to PDLIM2
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Dog, Human, Monkey
  • 免疫原

    Recombinant full length Human PDLIM2 produced in HEK293T cells (NP_067643).

  • 阳性对照
    • HEK293T cell lysate transfected with pCMV6-ENTRY PDLIM2 cDNA; HepG2, A549, COS7, Jurkat, MDCK and MCF7 cell extracts; Human tonsil tissue; COS7 cells transiently transfected by pCMV6-ENTRY PDLIM2.
  • 常规说明Dilute in PBS (pH7.3) before use. Stable for 12 months from date of receipt.

性能

应用

Our Abpromise guarantee covers the use of ab119243 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/2000. Predicted molecular weight: 37 kDa.
IHC-P 1/150.
ICC/IF 1/100.

靶标

  • 功能Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity.
  • 序列相似性Contains 1 LIM zinc-binding domain.
    Contains 1 PDZ (DHR) domain.
  • 细胞定位Cytoplasm > cytoskeleton; Nucleus; Cytoplasm. Nucleus. May be partially nuclear and Cytoplasm > cytoskeleton. Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ34715 antibody
    • MYSTIQUE antibody
    • OTTHUMP00000162522 antibody
    • OTTHUMP00000205197 antibody
    • OTTHUMP00000205198 antibody
    • OTTHUMP00000205199 antibody
    • OTTHUMP00000205200 antibody
    • OTTHUMP00000205202 antibody
    • OTTHUMP00000205203 antibody
    • PDLI2_HUMAN antibody
    • Pdlim2 antibody
    • PDZ and LIM domain 2 (mystique) antibody
    • PDZ and LIM domain protein 2 antibody
    • PDZ-LIM protein mystique antibody
    • SLIM antibody
    • Stat-interacting LIM protein antibody
    see all

Anti-PDLIM2 antibody [10C4] 图像

  • All lanes : Anti-PDLIM2 antibody [10C4] (ab119243) at 1/500 dilution

    Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNA
    Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY PDLIM2 cDNA

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 37 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC203156)
  • All lanes : Anti-PDLIM2 antibody [10C4] (ab119243) at 1/500 dilution

    Lane 1 : HepG2 cell extract
    Lane 2 : HeLa cell extract
    Lane 3 : SVT2 cell extract
    Lane 4 : A549 cell extract
    Lane 5 : COS7 cell extract
    Lane 6 : Jurkat cell extract
    Lane 7 : MDCK cell extract
    Lane 8 : PC12 cell line extract
    Lane 9 : MCF7 cell extract

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 37 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC203147)
  • ab119243, at 1/150, staining PDLIM2 in paraffin embedded Human tonsil by Immunohistochemistry.
  • ab119243, at 1/100, staining PDLIM2 in COS7 cells transiently transfected with pCMV6-ENTRY PDLIM2 by Immunofluorescence.

Anti-PDLIM2 antibody [10C4] (ab119243)参考文献

ab119243 has not yet been referenced specifically in any publications.

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