Synthetic peptide corresponding to Human PDK4 aa 83-111 (internal sequence) conjugated to keyhole limpet haemocyanin.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.09% Sodium Azide
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Ammonium Sulphate Precipitation
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100. Detects a band of approximately 50 kDa (predicted molecular weight: 46 kDa).
1/10 - 1/50.
Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Ubiquitous; highest levels of expression in heart and skeletal muscle.
Belongs to the PDK/BCKDK protein kinase family.
Contains 1 histidine kinase domain.
Information by UniProt
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4 antibody
Anti-PDK4 antibody (ab71240)参考文献
This product has been referenced in:
et al. Muscle expression of a malonyl-CoA-insensitive carnitine palmitoyltransferase-1 protects mice against high-fat/high-sucrose diet-induced insulin resistance. Am J Physiol Endocrinol Metab 311:E649-60 (2016).
Read more (PubMed: 27507552) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"