概述

  • 产品名称Anti-PDK2抗体
    参阅全部 PDK2 一抗
  • 描述
    兔多克隆抗体to PDK2
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein of Human PDK2 corresponding to amino acids 10-300

  • 阳性对照
    • Jurkat cell lysate, Human skeletal muscle tissue.

性能

应用

Our Abpromise guarantee covers the use of ab103429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 46 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
  • 组织特异性Expressed in many tissues, with the highest level in heart and skeletal muscle, intermediate levels in brain, kidney, pancreas and liver, and low levels in placenta and lung.
  • 序列相似性Belongs to the PDK/BCKDK protein kinase family.
    Contains 1 histidine kinase domain.
  • 细胞定位Mitochondrion matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2 antibody
    • mitochondrial antibody
    • PDHK2 antibody
    • PDK2 antibody
    • PDK2_HUMAN antibody
    • Pyruvate dehydrogenase kinase isoform 2 antibody
    • Pyruvate dehydrogenase kinase, isozyme 2 antibody
    • Pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial antibody
    see all

Anti-PDK2 antibody 图像

  • Anti-PDK2 antibody (ab103429) at 1/100 dilution + Jurkat cell lysate at 35 µg

    Predicted band size : 46 kDa
  • ab103429, at 1/50 dilution, staining PDK2 by immunohistochemistry, in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.

Anti-PDK2 antibody (ab103429)参考文献

ab103429 has not yet been referenced specifically in any publications.

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