概述

  • 产品名称
  • 描述
    山羊多克隆抗体to PDI
  • 经测试应用
    适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    C-NLETTKKYAPVD

    , corresponding to internal sequence amino acids 340-351 of Human PDI

  • 阳性对照
    • Human Heart and Human Small Intestine tissue. Human Pancreas lysate

性能

应用

Our Abpromise guarantee covers the use of ab110195 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.01 - 0.03 µg/ml. Predicted molecular weight: 57 kDa.
ELISA 1/64000.
IHC-P Use a concentration of 3.75 µg/ml.

靶标

  • 功能
    Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.
  • 组织特异性
    Highly expressed in pancreas (at protein level).
  • 序列相似性
    Belongs to the protein disulfide isomerase family.
    Contains 2 thioredoxin domains.
  • 翻译后修饰
    The disulfide-linked homodimer exhibits an enhanced chaperone activity.
    Glycosylated.
  • 细胞定位
    Endoplasmic reticulum lumen.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Pancreas specific protein disulfide isomerase antibody
    • Pancreas-specific protein disulfide isomerase antibody
    • Pancreatic protein disulfide isomerase antibody
    • PDA2 antibody
    • PDI antibody
    • PDIA2 antibody
    • PDIA2_HUMAN antibody
    • PDIp antibody
    • PDIR antibody
    • Protein disulfide isomerase A2 antibody
    • Protein disulfide isomerase antibody
    • Protein disulfide isomerase associated 2 antibody
    • Protein disulfide isomerase family A member 2 antibody
    • Protein disulfide isomerase pancreatic antibody
    • Protein disulfide-isomerase A2 antibody
    • Rho GDP dissociation inhibitor gamma antibody
    see all

图片

  • ab110195 at 3.75 µg/ml staining PDI in Human Heart Formalin-Fixed, Paraffin-Embedded tissue.
  • ab110195 at 3.75 µg/ml staining PDI in Human small intestine Formalin-Fixed, Paraffin-Embedded tissue.
  • Anti-PDI antibody (ab110195) at 0.03 µg/ml + Human Pancreas lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 57 kDa

文献

ab110195 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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