概述

  • 产品名称Anti-PDHX抗体
    参阅全部 PDHX 一抗
  • 描述
    兔多克隆抗体to PDHX
  • 经测试应用适用于: IHC-P, WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide (Human) conjugated to KLH, from the C-terminal region of human PDHX.

  • 阳性对照
    • mouse heart tissue lysate, human breast carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab71325 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100.
WB 1/100 - 1/500. Detects a band of approximately 54 kDa (predicted molecular weight: 54 kDa).
ELISA 1/1000.

靶标

  • 功能Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.
  • 疾病相关Defects in PDHX are the cause of pyruvate dehydrogenase E3-binding protein deficiency (PDHXD) [MIM:245349].
  • 序列相似性Belongs to the 2-oxoacid dehydrogenase family.
    Contains 1 lipoyl-binding domain.
  • 细胞定位Mitochondrion matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Dihydrolipoamide dehydrogenase binding protein of pyruvate dehydrogenase complex antibody
    • Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex antibody
    • DLDBP antibody
    • E3 binding protein antibody
    • E3-binding protein antibody
    • E3BP antibody
    • Lipoyl containing pyruvate dehydrogenase complex component X antibody
    • Lipoyl-containing pyruvate dehydrogenase complex component X antibody
    • mitochondrial antibody
    • ODPX_HUMAN antibody
    • OPDX antibody
    • PDHX antibody
    • PDX 1 antibody
    • PDX1 antibody
    • Pro X antibody
    • proX antibody
    • Pyruvate dehydrogenase complex component X antibody
    • Pyruvate dehydrogenase complex lipoyl containing component X antibody
    • Pyruvate dehydrogenase complex, E3 binding protein subunit antibody
    • Pyruvate dehydrogenase protein X component antibody
    • Pyruvate dehydrogenase protein X component mitochondrial antibody
    see all

Anti-PDHX antibody 图像

  • Human breast carcinoma tissue with ab71325 at 1/50 dilution. DAB staining.
  • Anti-PDHX antibody (ab71325) at 1/100 dilution + mouse heart tissue lysate at 12.5 µg

    Predicted band size : 54 kDa
    Observed band size : 54 kDa
    Additional bands at : 32 kDa,35 kDa. We are unsure as to the identity of these extra bands.

Anti-PDHX antibody (ab71325)参考文献

ab71325 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab71325.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"