Anti-PDHX抗体(ab31283)

概述

• 产品名称Anti-PDHX抗体
  参阅全部 PDHX 一抗
• 描述
  山羊多克隆抗体to PDHX
• 特异性This antibody is expected to recognise all reported isoforms.
• 经测试应用适用于: WB, ELISA, IHC-Pmore details
• 种属反应性
  与反应: Human
  预测可用于: Mouse, Rat, Chicken, Cow, Dog, Chimpanzee
• 免疫原

  Synthetic peptide corresponding to Human PDHX aa 496-500 (C terminal).
  Sequence:

  C-KSFKANLENPIRLA

  
  Database link: O00330
  Run BLAST with Run BLAST with
• 阳性对照
  • Human pancreas lysate. Human pancreas tissue sections.

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• 存储溶液Preservative: 0.02% Sodium Azide
  Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
• Concentration information loading...
• 纯度Immunogen affinity purified
• 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• 克隆多克隆
• 同种型IgG
• 研究领域
  • Signal Transduction
  • Metabolism
  • Energy Metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Metabolism
  • Types of disease
  • Cancer

相关产品

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)
• Positive Controls
  • Human pancreas tissue lysate - total protein (ab29816)

应用

靶标

• 功能Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.
• 疾病相关Defects in PDHX are the cause of pyruvate dehydrogenase E3-binding protein deficiency (PDHXD) [MIM:245349].
• 序列相似性Belongs to the 2-oxoacid dehydrogenase family.
  Contains 1 lipoyl-binding domain.
• 细胞定位Mitochondrion matrix.

• Target information above from: UniProt accession O00330 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 423154 Chicken
  • Entrez Gene: 8050 Human
  • Entrez Gene: 27402 Mouse
  • Entrez Gene: 311254 Rat
  • Omim: 608769 Human
  • SwissProt: O00330 Human
  • SwissProt: Q8BKZ9 Mouse
  • Unigene: 502315 Human

  • Unigene: 315011 Mouse

  see all
• 别名
  • Dihydrolipoamide dehydrogenase binding protein of pyruvate dehydrogenase complex antibody
  • Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex antibody
  • DLDBP antibody

  • E3 binding protein antibody
  • E3-binding protein antibody
  • E3BP antibody
  • Lipoyl containing pyruvate dehydrogenase complex component X antibody
  • Lipoyl-containing pyruvate dehydrogenase complex component X antibody
  • mitochondrial antibody
  • ODPX_HUMAN antibody
  • OPDX antibody
  • PDHX antibody
  • PDX 1 antibody
  • PDX1 antibody
  • Pro X antibody
  • proX antibody
  • Pyruvate dehydrogenase complex component X antibody
  • Pyruvate dehydrogenase complex lipoyl containing component X antibody
  • Pyruvate dehydrogenase complex, E3 binding protein subunit antibody
  • Pyruvate dehydrogenase protein X component antibody
  • Pyruvate dehydrogenase protein X component mitochondrial antibody

  see all